1. G- quadruplex is a special structure formed by telomere.

2. Telomere is at the end of the chromosome in eukaryotic cells and protects chromosomes.

3. Unchecked telomere loss by HSC, meanwhile, would appear to play a significant role in the pathogenesis of bone marrow failure, as observed in the condition dyskeratosis congenita.

4. Overall, the study participants had an average telomere loss of 21 nucleotides ( structural units ) per year.

5. Telomere locates on the terminal of DNA containing repeat DNA sequence.

6. The telomere is like a cellular clock, because every time a cell divides, the telomere shortens.

7. Untucked, a single- stranded telomere end is vulnerable to fusion with other single- stranded ends.

8. Objective To evaluate the role of telomere and DCC in tumor transformation and progression.

9. Telomere research is considered to be one of the most exciting areas in biomedical science and last year the Nobel Prize in medicine was shared between three scientists who are pioneers in the field.

10. Telomere function is one of the factors that determine radiosensitivity of cells and whole organism.

11. Telomere elongation in induced pluripotent stem cells from dyskeratosis congenita patients.

12. We summarize the present research of telomerase and telomere and their applications on ocular disease.

13. Can telomere maintenance be eliminated effectively ( and selectively ) enough by more tractable approaches?

14. Considering the risks of telomere - extension therapy, he thinks that scientists have bigger fish to fry.

15. Conclusion Telomere reduction and telomerase activation are critical factor during oncogenesis.

16. Leukocyte telomere length (LTL) reflects not only chronologic age but also the burden of disease. We hypothesized that LTL would be decreased in children with OSA.

17. Each segment of a telomere is like a ticket that gives it permission to divide.

18. Researchers estimate that telomere maintenance activity occurs in about 90 % of human cancers.

19. Telomere length and telomerase activity are important factors in the pathobiology of human disease.

20. ALT and TA mechanisms are dominant maintenance mechanisms of the telomere length.

21. Objective: The effect of DNA demethylation on aging process and telomere length was studied.

22. Pachytene FISH results showed that most of chromosome ends possess the telomere tandem repeats[sentencedict .com], but the signals on different chromosomes were not the same in intensity.

23. Some investigations on the ciliated protozoan have provided the insights into the mechanism of ribozymes, self-splicing RNA, telomere structure and function, DNA sequence reorganization and so on.

24. Telomere and telomerase are the focus of modern biological study. There are close relationships among telomere loss and cell ageing, activation of telomerase, cell senescence and immortalization.

25. Therefore, TRF 2 may protect chromosome ends by maintaining the correct structure at telomere termini.

26. The "hand" is the last 100 to 200 bases of the telomere, which are single-stranded , not paired like the rest.

27. Telomerase system is the genetic name of telomerase and telomere.