1. METHODS: The diabetic rat model was made with alloxan.

2. Model of DPN rats were made with alloxan.

3. METHODS:The model of alloxan diabetic mice was established to determined the activities of enzymes of antioxidant and ATP, and the contents of MDA, NO and glycogenesis.

4. Methods Normal and alloxan diabetic mice are used. Determining their blood glucose by means of o-Toluidine method (O-T).

5. The diabetic mice induced by alloxan were fed tea polysaccharides for 6 weeks, and observed the changes of the level of blood glucose and the activity of glucokinase in liver.

6. Results The Maize tassel saponin could reduce the hyperglycaemia caused by alloxan and adrenaline.

7. An experimental diabetes model was produced by intraperitoneal injection of alloxan. Blood glucose, liver glucokinase and liver glycogen contents were measured.

8. The effect of Melatonin on pituitary - adrenal axis of rats during inducing diabetes with alloxan was observed.

9. Conclusion TSJN has significant preventive and therapeutic effects on diabetic nephropathy rats induced by alloxan and achromycin.

10. METHODS Experimental observation was performed by using various diabetic mice induced by Alloxan, adrenalin, etc.http://

11. Glucose tolerance experimental results showed the saponin remarkably improves glucose tolerance of alloxan diabetic mice.

12. The mice model with diabetes and hyperlipidemia was established through the injection of alloxan and the feeding of high-fat food. The model mice were administrated with Russula polysaccharide.

13. Objective : To investigate the bone architectural changes on osteoporosis in diabetes mellitus rats induced by alloxan.

14. Objective : To make the model of diabetic gastroparesis ( DGP ) with the alloxan and libosch ( rehmannia glutinosa ) .

15. Oral administration of IBP resulted in significant glucose lowering in two mouse models of diabetes induced by Alloxan and Dexamethasone.

16. Objective : To observe the effects of Syzygium jambos Linn . seed extract ( SjSE ) on alloxan diabetes.

17. Results: The water extract of Prunella vulgaris L. decreased the postprandial hyperglycemia for the amylum tolerance test in normal and alloxan diabetes mellitus ICR mice.