1. OBJECTIVE To approach the feasibility of replacing pyrogen test with bacterial endotoxin test (BET) by analysing the interference of the injection to Limulus Amebocyte Lysate (LAL).

2. Conclusion Examination the pyrogen of the Safflower injection by the bacteria endotoxin test is not feasible.

3. It is concluded that leukocytic pyrogen acts directly on the thermoregulatory mechanism of the anterior hypothalamus to cause fever.

4. The bacterial endotoxins test may pyrogen test in detection GanFuTai for injection.

5. No significant fever of rabbit was observed in pyrogen test.

6. Methods: The methods of bacterial endotoxins test and pyrogen test in Chinese pharmacopeia 2000 were used.

7. In order to know the pyrogen in the disposable syringes and the repeatedly used glass syringes, Limulus Amebocyte Lysate test was used to carry out batch examination.

8. CONCLUSION: Bacterial endotoxin test could be used for pyrogen test of fructose diphosphate injection.

9. OBJECTIVE:To approach the feasibility of replacing pyrogen test by bacterial endotoxin test(BET)in assaying the injectio puerarin.

10. Conclusions: Bacterial endotoxin test could be used for pyrogen test of cefotaxime sodium.

11. The Pyrogen test is a method to test the existence of pyrogens by using rabbits.

12. Pyrexia is an effect due to pyretic cytokine and negatively regulating factors, the reaction is about the regulatory increasing of temperature caused by the response of pyrogen from the body.

13. Unique inner screw vapor free stage separation system , can clear toxin ( pyrogen ) in bacteria more thoroughly.

14. Conclusion The bacterial endotoxin test for Troxcrutin and Sodium Chloride Injection can replace the pyrogen test.

15. Objective To introduce a method to study the bacterial pyrogen in compound glycerin injection.

16. Evaluated the biocompatibility through the experiments including a cute systemic toxicity test, pyrogen, intracutaneous test and long-term muscle and bone implant test.

17. METHODS The interference function of secnidazole to TAL was investigated precisely by kinetic turbidimetric technique, and the results were compared with those of pyrogen method.

18. Conclusion: The bacteria endotoxin test can be used to monitor pyrogen in Sotalol Hydrochloride injection.

19. Aim To determine whether bacterial endotoxins test(BET) can replace the pyrogen test for the piperacillin sodium injection.

20. Conclusion: The bacterial endotoxin test can be used for the controlling pyrogen of CSI.

21. Objective : To establish a bacterial endotoxin testing method for monitoring pyrogen of compound sodium acetate injection.

22. The reproductive conditions of anti - lymphocyte immunoglobulin ( ALG ) semi - finished product unqualified in pyrogen were studied.

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23. Conclusion The bacterial endotoxins test can replacement the rabbit method for pyrogen test.

24. Conclusion The bacterial endotoxins could be used for this specimen instead of pyrogen test, and the result was the same as rabbit test.

25. Objective To determine the bioactivity of Luteinizing hormone(LH), follicle stimulating hormone(FSH), abnormal toxicity and pyrogen of highly purified FSH product.

26. Conclusions: Puerarin injection must be injected slowly and iv drip in Pyrogen test and clinical application.

27. Results: Chitosan membrane showed no toxicity and did not cause hemolysis, pyrogen or hyperergia.

28. CONCLUSION Bacterial endotoxin test can be used in place of the rabbit pyrogen test for monitoring bacterial endotoxin of procaine hydrochloride for injection.

29. CONCLUSION The jel method of bacterial endotoxin test can be used to pyrogen test the endotoxin in recombinant human erythropoietin injection instead of rabbit.

30. Conclusion: The bacterial endotoxins test can be used instead of pyrogen test for tinidazole injection.

31. Objective To establish bacterial endotoxin test of Cytidine Disodium Triphosphate Injection instead of pyrogen method.

32. Objective : To establish a method of bacterial test to Nizatidine injection and substitutethe pyrogen test.

33. Conclusion: It is feasible for bacteria endotoxin test instead of pyrogen test.

34. Where pyrogen test at present national pharmacopoeia statutory check for this is still a rabbit.

35. Methods: The bacterial endotoxins test was compared with pyrogen test.

36. Hartung's alternative pyrogen assay is licensed by a nonprofit group to Charles River Laboratories in Massachusetts.

37. Objective: To establish bacteria endotoxin test for monitoring pyrogen in netilmicin sulfate of glucose and sodium chloride injection( NGS).

38. Conclusion: Elemene Emulsion injection can be examined by bacterial endotoxin test instead of the pyrogen test.