1. Conclusion Erythroderma of unknown origin is mostly related to insidious malignancies and drug reactions.

2. Universal erythroderma, generally accompanied by scaling, may be associated with malignancy, usually lymphoma.

3. Methods Clinical data from 128 cases of erythroderma were retrospectively analyzed.

4. Erythroderma can be the skin manifestation of these syndromes, or occurs alone.

5. Objective To study the causes of erythroderma , the prognosis of patients and the influencing factors.

6. It is important to differentiate erythroderma induced by drugs from that b...

7. The erythroderma may be related to delayed hypersensitivity reaction as a result of decreased immunological activity.

8. Ocular complications in generalized erythroderma and the possible contributing factors will be discussed.

9. Methods: Clinical data from 120 cases of erythroderma were retrospectively analyzed.

10. Exfoliative erythroderma is a skin disorder with complicated etiopathogenesis as well as unknown pathogenesis.

11. It is important to differentiate erythroderma induced by drugs from that by other causes.

12. This paper reports the ultrastructural changes of the skin and lymphonodes from 5 patients with erythroderma of unknown cause.

13. Recent studies on adhesion molecules, cytokines and their receptors,() functional mutation of chromosome DNA have provided new insights into the pathogenesis of exfoliative erythroderma.

14. A 48 years old man was presented HIV infection with erythroderma, he had been diagnosed with diabetes about 10 years ago.

15. Along with the development and application of new drugs, the incidence of drug-induced erythroderma tends to increase, so does the number of sensitizing drugs.

16. We report a case with the clinical diagnosis of generalized erythroderma by dermatologist.

17. The inappropriate treatments(34.4%) were the main factor in inducing and aggravating erythroderma .