1. Controversy about essential hypertension has waxed and waned for a century, and what is orthodox today may change with time.

2. Essential hypertension is often associated with an augmented proximal reabsorption of sodium and uric acid.

3. Essential hypertension is a common cardiovascular disease. Its pathogenesy is still not clear at present.

4. Background:Essential hypertension (EH) is a complex and polygene genetic disease.

5. About hundreds of genes related to essential hypertension had been selected till now.

6. Approximately 30 % of cases of essential hypertension are attributable to genetic factors.

7. Essential hypertension, which is common in population anetiology and the medical therapy is predominantly used.

8. Objective:To examine the effect of Nifedipine Controlled Released Tablets and Lisinopril on renal function in patients with essential hypertension(EH).

9. Objective: To identify the association of M235T polymorphism of angiotensinogen (AGT) gene with essential hypertension complicated by brain infarction in Chinese Han population.

10. Fosinopril in the conclusion of the step-down at the same time, improve essential hypertension in patients with heart rate variability.

11. Objective To study the clinical significance of the changes of von willebrand factor(VWF) and D-dimer(D-D) in patients with 2-type diabetes mellitus(2-DM) and with 2-DM and essential hypertension(EH).

12. Objective To evaluate the safety of combination therapy with amlodipine and terazosin in middle aged and old male patients with essential hypertension.

13. AIM: To evaluate the long - term changing tendency of age distribution and the incidence of cardio- cerebral vessels in patients of essential hypertension.

14. Objective To observe the changes of tissue factor pathway(TFP) and tissue factor pathway inhibitor(TFPI) in essential hypertension and study the effects of enalapril and terazosin.

15. Objective To investigate the change of Chronotropic action and heart rate variability(HRV) in patients with essential hypertension(EH).

16. The plasma levels of atrial natriuretic factor (ANF) and prekallikrein(PK) were measured in Fatients with essential hypertension and in health subjects as a control.

17. Objective:To investigate the actions of Neuropeptide Y(NPY) and Neurotensin(NT) in the development of essential hypertension(EH), and the possible antihypertensive mechanism of benalapril.

18. Objective To investigate the clinical significance of changes of serum procollagen level in patients with essential hypertension (EH).

19. Results: 1) Of 4514 in-patients with hypertension, there were 83.81% of essential hypertension and 17.94% of secondary hypertension.

20. Objective To explore the curative effects of health education combined with Hypotensor treatment for essential hypertension.

21. Objective : To investigate the major effects of adrenotenin on the target organs in essential hypertension patients.

22. Objectve:To detect intrarenal arterial blood flow spectral parameters of essential hypertension(EH) with left ventricular hypertrophy(LVH)by Duplex color Doppler.

23. Objective: To study the relativity of insulin resistance(IR), hyperinsulinism(HI) and syndrome differentiation typing(SDT) in essential hypertension(EH).

24. Objective To investigate whether the angiotensinogen AGT(M235T) gene polymorphisms might be implicated in essential hypertension(EH) in Sichuan Hans population.

25. Objective:To investigate whether angiotensinogen(AGT)gene M235T variant is associated with essential hypertension(EH)in Chinese.

26. Effect of Irbesartan and Benazpril Combinationon Treatment on Micr oalbuminuria, Cretinine Clearance Rate, and Serum Cretinine in Patients with Essential Hypertension.

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27. Objective To explore the mechanism of enalapril for inversing aberrant hemorrheology and micro - circulation in essential hypertension.

28. Objective:To study the association between M235T variant of angiotensinogen gene (AGT) and familial essential hypertension(EH).

29. Objective:To determine artery buffering function at different artery segments in normotensive subjects and patients with essential hypertension.

30. Linkage analysis of cytokine and cytokine - related receptor gene loci and essential hypertension in Chinese.

31. Purpose To observe the effect of nape acupuncture on essential Hypertension.

32. Human essential hypertension is a complex polygenetic disorder which is thought to be determined by complex interactions between genetic predisposition and environmental factors.

33. Objective:To evaluate the cardial reserve function of an essential hypertension patient with left ventricular hypertrophy(LVH)by exercise treadmill test.

34. Objectives: To study the association between M235T allele polymorphism in exon 2 of angiotensinogen(AGT) gene and essential hypertension(EH).

35. Objective To observe the antihypertensive efficacy of celiprolol in patients with essential hypertension and compare with that of atenolol.

36. Objective:To investigate the relationship among essential hypertension, plasma renin activity (PRA) and angiotensinogen(AO).

37. Objective The pathogenesis of essential hypertension ( EH ) is not fully understood as yet.

38. Conclusion:The intrarenal arteries of in essential hypertension patients with LVH were in a state of low systolic, diastolic flow velocity and high renal vascular resistance.

39. AIM: To observe the effects of lisinopril in the treatment of essential hypertension (EH) with insulin resistance.

40. Age, systolic blood pressure and heart rate had close relationship with distensibility of large arteries in patients with essential hypertension.

41. Objective To assess the efficacy of low - dose Nifuda and Betaloc combination for essential hypertension.

42. Results: 109 cases of essential hypertension got 86.2 % total efficiency.

43. Objective:To investigate the genetic predisposition of the encoding genes for angiotensin-converting enzyme (ACE) and angiotensinogen (AGT) in essential hypertension (EH) in Chinese Han population.

44. The pathogenetic progression of essential hypertension is closely related to large artery remodelling.

45. It is accepted that essential hypertension is the one that is associated with multiple genes. Research shows that almost 60% of the hypertensive patients are salt-sensitive.

46. Objectives To evaluate the clinical significance of serum procollagen type I carboxy terminal peptide (PIP) in patients with essential hypertension (EH).

47. Objective To investigate the relationship between essential hypertension and carotid atherosclerosis.

48. Objective To study the changes and clinical significance of bilateral cerebral electrical admittance plethysmogram in senile patients with essential hypertension.

49. Endothelin - 1 contributes to increased systemic vascular resistance, vascular remoulding,() left ventricular dysfunction and renal impairment in essential hypertension.

50. This article summarized the mechanism of neurovascular decompression for essential hypertension and the operative courses.

51. Aim To investigate the role of total bile acid ( TBA ) and uric acid ( UA ) in pathogenesis of essential hypertension.

52. Aim:To compare the efficacy and side effect of domestic carvedilol and labetalol in the treatment of essential hypertension.

53. Objective : To investigate the changes of serum adiponectin ( APN ) content in patient with essential hypertension ( EH ).

54. Objective:To assess the compliant properties of the Common Carotid Artery(CCA)in healthy subjects and patients with essential hypertension based on strain-strain rate imaging.

55. Several drugs currently used in the treatment of essential hypertension act by inhibiting sympathetic vasoconstrictor tone.

56. Objective To explore cause of adverse events in patients with essential hypertension treated with anti - hypertension drugs.

57. Essential hypertension (EH), a complex polygenic disease,[http:///essential hypertension.html] is considered to the result of the genetic interaction of multiple gene alterations in concert with environmental factors.

58. Objective To investigate whether there are as sociations between missense mutation of renin gene and essential hypertension(EH).

59. OBJECTIVE To investigate the effects of tanshinone on peripheral blood monocytes(PBMC)activation in patients with essential hypertension(EH)during early stage of the diseased course.

60. Objective To study the effects of changes of neuropeptide Y(NPY) and neurotensin(NT) concentrations in plasma and their ratio imbalance on the incidence of essential hypertension (EH).