(1) Objective:To find out infection of coagulase -negative staphylococcus and their multiple drug resistance status and control nosocomial infections caused by CNS.

(2) To study the influence of slide coagulase test on determining the staphylococcus aureus (SA) with GPI assay.

(3) Objective To evaluate the "Staphylococcus aureus" coagulase tests with different plasma anticoagulants and different test methods.

(4) Among them Staphylococcus aureus (SA) and coagulase negative staphylococci (CNS), meticillin resistant SA (MRSA) and meticillin resistant CNS (MRCNS) accounted for 79.6% and 85.7%, respectively.

(5) Results The altered DNA sequence of coagulase in 1 strain of S . aureus was found.

(6) Coagulase negative staphylococci are the commonest blood culture isolate from infants on neonatal intensive care units.

(7) Results The most common pathogens were pseudomonas aeruginosa(11.63%), coagulase negative staphylococci (11.11%) and candida albicans(9.67%).

(8) Coagulase negative staphylococci accounted for 81.2% of allinfectionsin this series (Table 2).

(9) Objective To induce vancomycin-resistantant S. aureus in vitro and to observe the changes of coagulase gene sequences of S. aureus and its relationship with vancomycin resistance.

(10) The proportion of gram-negative bacillus and E coli were increasing in total causative pathogens annually, coagulase negative staphylococcus was decreasing year by year.

(11) OBJECTIVE To study the distribution of drug-resistant gene of meticillin-resistant coagulase negative Staphylococcus(MRCNS) in children septicemia.

(12) The most common bacteria isolated from the conjunctiva are small numbers of coagulase - negative staphylococcus and diphtheroids.

(13) Objective To invetigate the condition of erm genes in methicillin resistant coagulase negative staphylococci ( MRCNS ).

(14) OBJECTIVE To study the distribution and drug resistance of meticillin-resistante coagulase negative Staphylococcus(MRCNS) in neonate septicemia for rational use of antibiotics in clinic.