1. Frequent osteoclast - like giant cells are present.

2. Results: Caseification, osteoclast hyperplasia and bone destruction were found in the location of Mt sonicate injection.

3. The osteoclast lies next to bone, while the megakaryocyte lies out in the middle of the marrow.

4. Results: Osteoclast and their progenitor cells underwent apoptosis after exposure to alendronate in vitro.

5. Summary of Background Data. Osteopetrosis is characterized by osteoclast dysfunction, impaired bone resorption, and poor bone remodeling.

6. Immunohistochemistry, the osteoclast - like giant cells were positive for CD 68. Vim, α1 - ACT and negative for CK, EMA.

7. In contrast, it decreases osteoclastic cell differentiation and resorbing activity, and increases osteoclast apoptosis.

8. The purified protein has been used for induced osteoclast differentiation in vitro.

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9. Mononucleated osteoclast reached peak level at 3 days after tooth movement, while multinucleated cells reached peak level at 5 days.

10. Osteoblast and osteoclast activity in a malignant infantile osteopetrosis patient following bone marrow transplantation.

11. Conclusions The increased number of osteoclast might be one of the reasons for the development of osteoporosis in rat with T1DM, while Alendronate can inhibit in vitro OLCs formation in these rats.

12. Its differentiation effect on inhibiting osteoclast was assessed with statistics analysis.

13. Objective To determine whether leukotriene B4 (LTB4) could directly stimulate human osteoclast differentiation and activation independent of RANKL (ODF).

14. With the similar histological change, alendronate treatment group, due to inhibition of the osteoclast cells, needs statistically greater pull out strength than estrogen treatment group does.

15. The final result of bone resorption which was caused either by local or systemic factors was related to the abnormal function of osteoclast.

16. Bone is a complex tissue composed of several cell types and the two major of them responsible for bone remodelling are osteoclast, which resorb bone, and osteoblast, which form new bone.

17. Object : The study a feasibility method of obtaining human osteoclast - like cells for purpose of further research.