1, Methylation of chromatin causes it to condense.

2, AIM To investigate the relation between methylation of plasma thrombomodulin ( TM ) gene promoter and coronary heart disease ( CHD ).

3, BACKGROUND: Gene promoter methylation is an epigenetic event leading to gene silencing.

4, In the histone code the methylation target is known as H 3 K 9, where K stands for lysine.

5, In malignant cell the pattern of DNA methylation, as well as the set of DNA methyltransferase activities, differs from that in normal cell.

6, Recent studies on DNA methylation and its regulatory enzymes, seem hot to researches of epigenetics.

7, Some methods could also determine the pattern of methylation or the degree of pectins acetylation.

8, In this paper, the methylation of biphenyl to 4-methylbiphenyl (4-MBP) over the zeolite catalysts was studied.

9, Analysis of the resulting cytosine methylation patterns with the highest resolution is achieved after sodium bisulfite treatment, deaminating nonmethylated cytosines to uracil.

10, Furthermore, CpG methylation within the NF 2 promoter region was thoroughly analyzed.

11, In the end, the effects of methylation on the properties of uracil and adenine-uracil base pair have been investigated.

12, This "methylation" of GR appears to make the individual more tuned in or sensitised to stress, meaning that they will react to it quicker both mentally and hormonally.

13, Frequencies of decrease in DNA methylation sites among cultivars were in this order: V27, V14, and R09, V27 showing more demethylation sites.

14, In this article, the methylation and tumor, methylation and hematologic diseases, methylation detection methods,[http:///methylation.html] demethylation therapy in leukemia and so on are reviewed.

15, The team showed that CDK1 short-circuits EZH2-mediated methylation by attaching a different chemical group consisting of one phosphate and three oxygen atoms to EZH2, a process called phosphorylation.

16, Much of the review discusses studies of mercury methylation and the opposite process demethylation .

17, The team looked at methylation, in which a methyl group is placed onto cytosine in DNA sequences.

18, The most widely known methylation inhibitors are cytidine analogues. However, due to their substantial cytotoxicity, they are limited in their application.

19, Methylation analysis showed there were different levels of methylation in Zizania latifolia, but high level of methylation in rice.

20, Lanes 1, 3 and 5 demonstrate, that there is no influence of the nucleotide sequence on protein methylation.

21, This indicates that the transcriptional activity of the transgenic mice is not reflected in the methylation state of the transgenes.

22, SET domain proteins contain conserved SET domains, which intensively involved in histone methylation.

23, The invention provides a catalyst used for preparing para-xylene and low-carbon olefin movable bed by selective methylation of toluene with methanol.

24, Using MSP, PCR-SSCP and denaturing PAGE gel electrophoresis, we interpret the mutation, deletion and methylation of RUNX3 gene in the level of DNA in gastric carcinoma.

25, Z associates with functional regulatory elements, and CTCF marks boundaries of histone methylation domains.

26, The methods about indirect Chloromethylation of Polystyrene are discussed, and the conditions and factors affecting the reactions of chloro- methylation also discussed here.

27, If you look in the normal population and ask what fraction of people have [a defect in methylation in the gene encoding insulin-like growth factor 2] it's about 5 percent.

28, S-adenosylmethionine is required as methyl donor for both arsenic metabolism and DNA methylation.

29, This article will review research advances on brain tumor methylation.

30, Phenol was used as a primary material. The diethylstilbestrol was obtained by the Fries Rearrangement, methylation, bimolecular reduction, elimination of 1, 2-diol and demethylation.

31, Petrossian, T. Clarke, S. Methylation of DNA, protein, and even RNA species are integral processes in epigenesis.

32, The genomic DNA methylation tends to repress gene expression while demethylation or hypomethylation activates the gene expression.

33, It take for S-adenosylmethionine as methyl donor. DNA methylation has essential roles in many plant life processes.

34, Mercury methylation by microbes plays a key role in mercury biogeochemical cycle, and closely related with public health.

35, DNA methylation and its aberrance play an important role in the human development and tumorigenesis.

36, Using strain C514 as experimental strain, the factors that influenced C5-O methylation of avermectins were studied.

37, Core processes of epigenetic inheritance include DNA methylation, histone modification, nucleosome remodeling, nuclear dynamics and chromatin interaction with non-coding RNAs.

38, In addition, methylation and methyl rearrangement of arenes were mainly controlled by the abundance, source and evolution degree of soluble organic matter.

39, DNA methylation is an important epigenetic modification which regulates a number of biological processes.

40, Wetland has high Hg accumulation rate and methylation capacity. In wetland, redox condition and abundant organic carbon are favorable to methylation of Hg.

41, Chemical modification of PC-3 by periodate oxidation, partial acid hydrolysis, methylation, sulfation, PC-3 and its derivation were tested for anti-virus activities against Coxsackis B5.

42, Method 1,3,5-trimethylbenzene was selected as the start material. The final product was obtained in five steps, including two steps bromination, cyanidation, methylation and N-alkylation.

43, The analysis of DNA methylation in plasma applicate to noninvasive prenatal diagnosis.

44, Aim: To detect the methylation at the promoter P3 of human insulin-like growth factor II (IGF-II) gene in hepatocellular carcinoma.

45, The information in this study is important for its extensive utility in gene feature analysis and epigenomics including gene prediction and methylation chip design in different genomes.

46, We present here a database for DNA methylation data that attempts to unify these results in a common resource.

47, Oxidative methylation of toluol to styrene is a new process studied widely recently.

48, DNA methylation has also been found in premalignant lesions such as prostatic intraepithelial neoplasia[/methylation.html], but to a less extent compared with that in prostate cancer.

49, With this new set of tools, Luger and her colleagues did x-ray crystallographic and biophysical studies to see how methylation affects the structure of chromatin and nucleosomes.

50, Procaryotic M enzymes as model molecule play an important role in studying mechanism of methylation and demethylation.

51, Methods: Simvastatin was synthesized from lovastatin via several steps involving acetylization, methylation , hydrolytic decomposition and cyclization reactions.

52, Methoxyphenyl acetonitrile was synthesized from(4hydroxyphenyl)acetamide through methylation and dehydration. The total yield reached 76.5% and the purity 99.5%.

53, The 3,4,5 trimethoxybenzaldehyde is synthesized from p cresol in four steps of bromination, hydrolyzation, methoxylation, and methylation, with an overall yield of 53.

54, Researchers looked for - and found - a chemical change called DNA methylation in healthy tissue adjacent to breast tumors.

55, This article briefly discusses plant DNA methyltransferase, the mode and the loci of Methylation and the epigenetic phenomenon originated by DNA methylation.

56, METHODS Phase-transfer catalytic methylation and suitable method of aftertreatment were used. RESULTS The yield and content was both improved.

57, Methods: The target compounds were synthesized by methylation and acetylation, iodomethane as methylated reagent, acetic anhydride as acylated reagent.

58, In the 2-4 hour, the increasing speed of methylate shoot up and exceeded the level of demethylation. In the 4-16 hour, the level of methylation went to stable and kept on the higher level.

59, DNA methylation has a number of epigenetic functions, but the scientific interest has recently focused on the gene silencing effect methylation can have in eucaryotic cells.

60, METHOD: 1 Deoxy D ribose was prepared from D ribose via methylation, silylation, reductive cleavage and hydrolysis by a sequence of four high yield reactions.

61, Methods: Simvastatin was synthesized from lovastatin via acetylization, methylation, hydrolytic decomposition and cyclization reactions.

62, Objective To investigate the relationship between methylation of tumor suppressor gene and gastric cancer.

63, Clarithromycin was prepared from erythromycin A through oximation, protection, methylation and deprotection. The overall yield of clarithromycin was 40%.

64, It is ascertained that the PABA may be N - dimethylated using dimethyl sulfate as a methylation agent.

65, It was determined that a sample number of 12 was sufficient to represent the majority of genetic or epigenetic (in the form of DNA methylation) diversity for a given population of wild barley.

66, This article reviews the advances of researching relation between DNA methylation aberrance and transcription and tumorigenesis in the last decades, especially a recent breakthrough in cancer.