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单词 Mutation
例句
1) The protein contained a mutation.
2) The genetic material has suffered a mutation.
3) These plants carry the mutation for red flowers.
4) These cells carry a mutation affecting the prevention mechanism.
5) It is well known that radiation can cause mutation.
6) Scientists have found a genetic mutation that appears to be the cause of Huntington's disease.
7) They are free to evolve at the mutation rate.
8) Evolution requires genetic change, mutation.
9) Our random mutation is essential because it is unnecessary.
10) It strives for a mutation rate of zero.
11) Only Broadmeyer, as the creator of this mutation, knew the answer.
12) This does not rule out evolution by mutation and selection.
13) A second bug experienced a mutation that allowed it to make use of the acetate excreted from the first.
14) Its use of mutation and chance seems to occur within restraints; within an algorithm that we are still trying to decipher.
15) Mutation is random; natural selection is the very opposite of random.
16) The mutation has no functional significance and controls no traits, researchers say.
17) Whether his fainting goats were a new mutation or part of an older breed remains unclear.
18) Mutants show the effect of the mutation in their phenotype.
19) Mutation is almost guaranteed and one individual among billions is certain to draw the successful ticket in the genetic lottery.
20) Mutation could once be studied only in bacteria or in fruit flies.
21) Both patients described were heterozygous for the missense mutation at codon 200 of the prion protein gene.
22) In Celtic languages such as Welsh, there is a process of mutation affecting the beginning sound of a word, according to the word which comes before it.
23) That is, the rate of substitution equals the neutral mutation rate.
24) In any case, the effect occurred too rapidly to be accounted for by mutation accumulation.
25) The vital factor is that in each generation there is some small mutation which is an improvement, and which is conserved.
26) The brief respite before the pests could fight back reflects the wait for a mutation.
27) The genes that cause the elaborate ornament or long tail to appear are subject to random mutation.
28) Deletions of chromosome 17p are found in 75% of colorectal cancers and are highly correlated with mutation of the remaining p53 gene.
29) This is a worthwhile approach,(http:///mutation.html) though one should bear in mind that different mutagens give qualitatively different kinds of mutation.
30) To begin with, this was the only such pattern in existence, but then a new mutation arose.
1) The protein contained a mutation.
31) By far the shakiest part of the calculation is the average mutation rate.
32) The more elaborate the ornament, the more likely that a random mutation will make the ornament less elaborate, not more.
33) Alternatively, this mutation might lead to production of a protein that is only partly functional and causes a milder disease.
34) The concept of an advantageous mutation spurring evolution is the standard model with which evolutionists still work.
35) For the last 20 years researchers have been able to calculate genome sizes and mutation rates.
36) If the mutation creates or destroys a restriction site then this can be simply examined in the products of the reaction.
37) Immunocytochemistry can then be used as a marker of p53 mutation, although DNA sequencing remains the gold standard.
38) If this shows a lethal mutation it is classified as a presumed mammalian mutagen.
39) The mutation leads to change in the transcript level equilibrium.
40) The mutation rate is bound to place an upper limit on the rate at which evolution can proceed.
41) The use of immunohistochemical staining as a marker of point mutation has been critically reviewed by Wyndord-Thomas.
42) Direct DNA sequencing of the relevant amplification products in both patients was used to characterize each mutation.
43) The aim is to discover how far mutation has depressed survival and fertility below their optimal values.
44) It's one of the most rewarding attributes they possess - discovering and articulating the weird mutation in the human race.
45) One of the original bugs had undergone a mutation that caused it to excrete acetate, an organic chemical.
46) Over time, in a certain percentage of cells, that mutation caused further errors.
47) But in the 1980s, scientists found that a genetic mutation was responsible.
48) Was it feasible, was it remotely possible, that the mutation had some sort of driving force?
49) A clear example of a mutation altering development is the inherited genetic defect, sickle cell anaemia.
50) Perhaps gene therapy could prevent the mutation of the prion gene that causes hereditary brain disease.
51) Gerda could be searching for Kay to give him the therapy injection that will save him from the mutation disease.
52) Yet despite the handicap ensuing from the mutation, and contrary to observations in human pathology, the strain appears to be unaffected.
53) His only thought was to get away, away from those madmen, away from the mutation, away from the cathedral.
54) Loss of tumour suppressor function requires inactivation of both alleles, usually by chromosomal deletion or point mutation, or both.
55) Once a mutation that causes an abnormality is observed, it becomes possible to try and identify and isolate the gene.
56) Shaken free from its sand, a casting looked like nothing so much as a grotesque mutation of the final part.
57) Two out of 160 G418-resistant D3 clones were found to have the targeted mutation and clone 515 gave rise to germ-line chimaeras.
58) In splurge-weed, the new mutation can arise in any cell,(http:///mutation.html) in any branch of the plant.
59) Near neighbours in genetic space are animals that differ from one another by only a single mutation.
60) When a segregation distorter arises by mutation, it will spread inexorably through the population at the expense of its allele.
61) According to spy's theory, the Ardakkeans had been transformed - by some beneficial mutation, he theorized - into super-beings.
62) The most fundamental level of diversity generation is that of mutation, crossing over, recombination, and related genetic operations.
63) A minor mutation should be deemed an eccentricity and nothing more.
64) Living organisms have a similar tradeoff in deciding how much mutation and innovation is needed to keep up with a changing environment.
65) Where possible the purified proteins have been sequenced at the amino terminus to confirm the presence of the expected mutation.
66) Ray designed a system called Tierra that consisted of competing programs that were constantly being filled by mutation with small errors.
67) Discussion Overexpression and mutation of the p53 gene is now well described in large bowel cancer.
68) It follows that some process other than random mutation and selection must be involved.
69) Yes, this is the inverse of what is known as the mutation rate, and it can be measured.
70) Apart from point mutation, another way in which oncogenes can be activated is by over expression.
71) Although inconsistencies clearly exist, most studies of large bowel tumours show a very strong correlation between immunocytochemical positivity and p53 mutation.
72) One of the most remarkable observations concerning the mutant strain was the fact that it appeared very little affected by this mutation.
73) Ironically, a similar belief prevails today, in a slightly different mutation.
74) Moreover, mutation rates seem to change with the physiological state of the organism.
75) This will tend to apply to all the logs placed by any beaver bearing this particular mutation.
76) Mutation has to work by modifying the existing processes of embryonic development.
77) If mutagens like cosmic rays are present then all normal mutation rates are boosted.
78) Each digestion included a positive colorectal carcinoma or adenoma control known to contain a mutation at codon 12.
79) Nineth five percent of large bowel cancers showing loss of heterozygosity for 17p alleles also contain a point mutation.
80) Spontaneous and induced mutation occur with animals viruses.
81) AIM:To investigate gene mutation of patient with oligodontia.
82) Ion beam mutation has significant bio - effect.
83) Mutation are produced by a number of chemicals.
84) Biological variation resulting from recombination, mutation, and selection.
85) Deletion and mutation of CTCF is associated with cancer.
86) Editorial: World Mutation or Epochal Challenge?
87) The conclusion we obtained from the experiment was that the missense mutation of .
87) is a online sentence dictionary, on which you can find excellent sentences for a large number of words.
88) Abstract: Safety rheology and mutation are new contents in the theory of safety science.
89) Wavelet transform has good localization feature and multiresolution analysis, and capacity of detecting local signal mutation.
90) In order to explore the effect of precedent mutation on the sensitivity to mutagens the mutants resistant to 6 thioguanine (6 TG) were selected by 6 TG using gene mutation assay in V79 cells.
91) In BCR - fusion gene negative myeloproliferative diseases, the discovery of JAK 2 V 617 F point mutation is an important landmark.
92) In non - coding region It'shows mutation of single nucleotide deletion or substitution.
93) Mutation of ENG gene can cause type 1 hereditary hemorrhagic telangiectasia ( HHT 1 ) .
94) A cruel twist of mutation among the Theelin led to genetic incompatibility among their own kind, dooming the species to extinction.
95) A mutant, TS-N-121 was obtained by mutation and plate screening from a parent strain Mycobacterium fortuitum MF2 , which could transform sterol into androstanedione as the main product.
96) Objective : To analyze G 6 PD gene mutation in 168 Cantonese G 6 PD deficient male infants.
97) NAFSA combines the niche technique and the simulated annealing method with AFSA. Moreover, the ideas of mutation operator and the automatic calculation of the niche radius are used in NAFSA.
98) We show that sodium channels with the missense mutation recover from inactivation more rapidly than normal and that the frameshift mutation causes the sodium channel to be non-functional.
99) Absreact: This experiment was conducted to study the influence of growth hormone receptor(GHR) gene mutation on the semen quality of sex-linked dwarf chicken.
100) By Xanthomonas Mutation screening activity eventually obtained a high specificity and high stability of the genetic traits of strains BT112.
101) In Ames assay the strains were TA98 and TA100, which were able to determine base pair substitutions and frameshift mutation respectively.
102) Mutation analysis in families with XLHED allows for genetic counselling, prenatal diagnosis and gene therapy.
103) People who have nutation this mutation need less sleep than other'sothers.
104) The mechanism of this albescent phenomenon was discussed, and regarded that the mutation of temperature sensitive mutant is probably mutually controlled by the nuclear gene and nuclear cytoplasm.
105) The evolution of the humanity includes some contradictions, such as, anamorphosis and mutation, essence and appearance, evolution and alienation.
106) HBV mutation is another important factor in addition to the hosts'immunologic response.
107) Objective To establish TK gene mutation assay using human lymphoblastoid cell line TK6 and to study the genotoxic mechanism of Vinblastine(VBL).
108) "The [mutation] rose to extremely high frequency in a relatively short time, implying that the selective force was quite strong, " Su says.
109) The mutation pattern of silver crucian carp was very complexional, as well as some loci did not follow the Stepwise Mutation Model.
110) Mutation analysis of BRCA 2 is laborious with the huge coding sequence and the diversity of mutations.
111) In order to maintain the diversity of population, the algorithm uses the IUPAC degenerate code for mutation.
112) The patient′s mother was the carrier of the heterozygosis mutation in X-chromosome.
113) Conclusion The results of the experiment show that menadiol sodium diphosphate has no mutation effects on the procaryotic cell in vitro.
114) Single strand conformation polymorphism (SSCP) essay and sequence analysis of the PCR product were used to ascertain the gene mutation.
115) Abnormities of SC resulting from genetic mutation can directly induce arrest of spermatogenesis in rat model.
116) Results Hereditary pancreatitis was a rare type of pancreatitis, with an estimated penetrance of 80 % , and was believed to be caused by a mutation in the cationic trypsinogen gene.
117) Objective To detect the mutation on exons 32,(http:///mutation.html)33 of Chinese the neurofibromatosis type 1 (NF1) gene.
118) Conclusbo : It'suggsts that ras gene aed p 53 gene mutation may be related with L - form infedtbo.
119) The team selected rice strains that have poor grain-filling and, following extensive genetic screening, found a mutation within a gene called GIF1 (Grain Incomplete Filling 1).
120) Missense mutation --- A mutation that changes a codon specific for one amino acid to specify another amino acid.
121) Objective:To assess the roles of single stranded conformation polymorphism(SSCP)and heteroduplex polymorphism(HET)in screening gene mutation.
122) The most drastic of the changes presently happening is the mutation from bipolarity to monopolarity.
123) A new fuzzy dynamic assessment based on mutation theory is proposed.
124) It's still controversial about the relationship of BRAF mutation with heredity, pre-existing pigment nevi , invasion and prognosis of MM.
125) This mutation makes it better adapted than the other four.
126) This article based on the mutation theory, proposes the application mutation theory optimal mine ventilation system synthesis appraisal.
127) Be in hospital, move the mutation that waits for an environment, what can cause gawkish symptom is exasperate, bring about melancholia shape to wait.
128) Organisms can also develop detoxication mechanism for excreting Al and the internal equilibrium protection mechanism by mutation, natural selection and self-organized latent energy.
129) Ras gene mutation in childhood AML was mainly found in M 2 , M 4 , M 5 subtypes.
130) This paper introduced an effect capillary zone electrophoresis method for screening of stevia mutation.
131) The method, mutation mechanism and characteristics of ion implantation were introduced.
132) The mutation was confirmed by allele specific PCR ( ASPCR ).
133) Another concept is to prevent drug resistance and optimal management of strategy was nucleoside resistance mutation.
134) Objective To identify the mutation gene of a Chinese family with ectopia lentis.
135) Conclusion N395K and I848T mutations are the causes of clinical phenotypes of these patients; L858, I848 and N395 may be the hot mutation spots of SCN9A gene in primary erythermalgia.
136) Conclusion Maybe there is no association with E237G gene mutation between asthma and atopy.
137) The human species: Homo Sapiens, was created by genetic mutation using the available primates and supplementing this base stock with their own genetic material.
138) All of the resistant viruses carried the same H275Y mutation, indicating resistance to oseltamivir but susceptibility to the second antiviral drug, zanamivir.
139) Besides, it showed that Turki had closest relationship with modern out Mongolia contrasted with the reported populations. And the 5 mutation sites of Turki were all hot mutation sites of Mongolian.
140) A hot spot is a DNA base pair (the individual units of DNA) that is especially prone to mutation.
141) At the same time, the information of flax biotechnology of anther culture, haploid breeding, utilization of somatic mutation, protoplasmic culture, gene transformation were introduced in detail.
142) Neurofibromatosis type 1 is a common autosomal dominant disorder with a high rate of penetrance. It is caused by the mutation of the tumor suppressor gene NF1, which encodes neurofibromin.
143) cells affected by mutation.
144) The two mutants arose from new gene mutation characterized by transformation and will be very useful in identification of new gene controlling peroxisome assembly from yeast.
145) This week hangs equestrian website to be centered at large website and study recreation website, have a vaulting horse among them particularly notable, it is " BAL of AV terminator mutation ".
146) This mutation was the same as those identified in MBC resistant field isolates of other phytopathogenic fungi, and there existed obvious negative cross resistance between MBC and diethofencarb(NPC).
147) The data suggested that the mutation allele of UGT2B7 could affect individual's susceptibility to bladder cancer in the case of benzidine occupational exposure.
148) FvL mutation may be a underlying pathogenicity of familial BCS.
149) Methods: Polymerase chain reaction ( PCR ),(http:///mutation.html) DNA direct nucleotide sequencing and RFLP were used in mutation analysis.
150) Many of the safeguards we use for encapsulation are really just there to prevent mutation. Once we tease apart those two concepts, a cleaner Java implementation emerges.
151) Missense mutation A point mutation that causes a change in one amino acid of a protein.
152) The crossover operation and mutation operation of decimal code genetic algorithm and its application in the optimal problem of nonlinear function are discussed in detail.
153) Mutation of CPAP induces a neuro-developmental disorder named MCPH (autosomal recessive primary microcephaly) that causes a great reduction in brain growth in human.
154) An international team of 16 scientists today reports the first direct measurement of the general rate of genetic mutation at individual DNA letters in humans.
155) Cells with Ras gene mutation or transformed by Ras become resistant to p 53 dependent apoptosis.
156) To prevent resorting mutation, TQ 111 strain was selected for UV mutagenesis strains with.
157) The polysaccharose content of nature Cordyceps sinensis was 8.92%. The polysaccharose content of UV mutation was 8.41%. The polysaccharose content of NTG mutation was 9.08%.
158) Tobacco increased significantly the mutation rate of Salmonella typhia and the formation rate of CHO colony.
159) It appears that, like the golden zebrafish , light-skinned Europeans also have a mutation in the gene for melanosome production. This results in less pigmented skin.
160) After the ventilation supercavity formed, the ventilation mutation distinctly influenced the form, the way of gas-leakage and the stability of cavity.
161) Some monilethrix has been reported to be associated with genetic mutations on human keratins. Mutation in DSG4 has also been reported.
162) Moreover, the sensors were able to detect the transient mutation in cells(such as, the mitochysis and death of cell)because of the response time shortened to microsecond.
163) Quantum NOT gate is used to realize quantum mutation to avoid premature convergence.
164) Biological and N-terminal amino acids analysis exclude the most common As type of genotypic mutation of albumins.
165) According to comparing the zymograms of isoelectrofocusing, the relationship of enzyme activity and energy metabolism, and the relationship of enzyme activity and gene mutation were studied.
166) All of the patients who had parkin gene deletion mutation had tremor, rigidity and bradykinesia, but athetosis and family history of PD were not found.
167) This algorithm includes clonal selection, hyper - mutation and receptor editing.
168) Methods HPRT gene mutation frequency was examined by the technique of multinuclear cell assay.
169) The deletion mutation and missense mutation of COL7A1 gene result in the specific mutation in patients with clinical symptoms.
170) The mutations in patients with factor V deficiency were identified including point mutation, frameshift mutation, deletion and insertion mutation.
171) Methods: Nine heterozygous mutation carriers and nine healthy controls were investigated.
172) It's plausible that millions of years ago a single mutation resulted in two different versions of the photopigment gene becoming located on the same X chromosome.
173) So far the discussion has centered entirely around mutation in the strict sense.
174) Conclusions The splicing mutation of COL7A1 gene is the underlying cause of and specific rather than common polymorphism for the family with dystrophic epidermolysis bullosa pruriginosa subtype.
175) The dilatation process of coal mass is depicted by 3 characteristic quantities , namely, volume compression, steady dilatation and dilatation mutation.
176) Many leukemic oncogenes form as a consequence of gene fusions or mutation that result in the activation or overexpression of a tyrosine kinase.
177) Conclusion:LP is an autosomal recessive disease,(http:///mutation.html) and the mutation of pathogenic gene of LP is rare in Chinese people.
178) Recent studies on adhesion molecules, cytokines and their receptors, functional mutation of chromosome DNA have provided new insights into the pathogenesis of exfoliative erythroderma.
179) People who have this mutation need less sleep than others.
180) Results A homozygous mutation at exon 13 of the proband was found by parallel TGGE. Homozygous and heterozygous mutations were also found in the family by parallel TGGE.
181) When scientists examined the pair's DNA, they found a mutation in a gene called DEC2, which governs cell production and circadian rhythm.
182) Strangely, in a few percent of the offspring of Lolle and Pruitt's mutants, one copy of hothead spontaneously reverted to the normal version, repairing its point mutation.
183) Bilateral prophylactic mastectomy or oophorectomy can reduce the incidence of breast cancer in BRCA mutation carriers.
184) ConclusionG 71 R gene mutation combined with G 6 PDdeficiency aggravates the degree of neonatal jaundice.
185) Low energy ion beam has broad prospect in the applications of physical mutation breeding techniques.
186) In this paper, we propose an improved evolutionary programming using a mixed strategy based on Gaussion mutation and single-point mutation, which is named SPCEP.
187) Up to date, on the bases of linkage analysis and cytogenetic analysis, the loci associated with microphthalmia have been identified and mutation analysis of the candidate loci are performed.
188) Technique of mutation breeding in gladiola was studied by means of electron beam.
189) Lastest, oversea researchers had found that there is one missense mutation high relative with NIDDM patients in GCG R gene.
190) A design of parity check matrix for Irregular LDPC codes based on per mutation matrix is proposed in this paper.
191) It has been widely applied gene analysis, detection of gene mutation and genetic disease.
192) The method of mutation breeding and the current research situation of Thiobacillus ferrous oxide are summarized, and some problems in the process of breeding are discussed.
193) This method can compete mastered knowledge inheriting by selection operation to former rules, can perform rules mutation operation by resemble degree computation.
194) Conclusion The model of Fgfr 3 Gly 374 Arg mutation causing achondroplasia in mice has been established successfully.
195) Conclusions These results can indicate that the spot mutation of ECR1 gene in young patients with malignancy may be related to immunopathological mechanism.
196) Genetic analysis showed that the drm 1 carries a single, recessive nuclear mutation.
197) The mutation rates of A. auricula basidiospores were about 0.05 to 0.19. The result showed that the mutagenic effects of laser on A. auricula were stronger than that of ultraviolet.
198) Gene mutation analysis was performed for patients with BH4 deficiency and their parents.
199) The algorithm makes fully use of initial value sensitivity and track ergodicity of chaos, overcoming the disadvantage of big searching dead zone existed in conventional chaotic mutation model.
200) Objective To identity the ABCD1 gene mutation in a Chinese family with X-linked adrenoleukodystrophy(ALD).
201) The symbol encoding style what was needed for the optimization apportion model was solved, and selection operator, cross operator and mutation operator were designed concretely .
202) In evolutionism, the borrowed concepts of mutation and sexual reproduction spawn the art.
203) Tyrosinase is the essential enzyme in melanogenesis . The mutation of tyrosinase gene causes albinism.
204) The theory of safety rheology and mutation and Murphy's Law solves the origin problems.
205) The sports illustrated cover girl or miss usa or genetic mutation or whatever she was?
206) Those researchers identified a mutation in FOXP 2 as the cause of the dyspraxia.
207) The Genetic Algorithm (GA) is a kind of global optimal searching algorithm based on Darwin's nature evolution theory and Mendel's genetics and mutation theory.
207) try its best to gather and create good sentences.
208) The couples were put into three groups depending on the DNA of the men: men without the gene mutation, men with one copy of the mutant gene and men with both copies of the mutation.
209) The work provided the direction for mutation to improve enzymatic specific activity and studying the mechanism of thermostability and thermophilicity.
210) Methods: Polymerase chain reaction-single strand conformation polymorphism(PCR-SSCP) was used to exclude known gene mutation of HGF from 2 familial gingival fibromatosis .
211) They showed that the mutation definitely reduces the number of malaria-causing Plasmodium vivax parasites, lessening the severity of the disease.
212) In this article, the growth regulating mechanism of chicken is discussed, The sex-linked dwarfism in chickens is due to the GHR gene mutation and point mutation and deletion are two main forms.
213) Finally, bifurcation points are extracted for different mutation regions using reassigned wavelet scalogram.
213) is a online sentence dictionary, on which you can find good sentences for a large number of words.
214) These results indicate that the mutation does not interfere with the ability of agrin to induce postsynaptic structures but that it dramatically perturbs the maintenance of the neuromuscular junction.
215) Genetics: Color mutation - The Hypo Boa is a Co - dominant or incomplete dominant trait.
216) Chromosomal mutation, called aneuploidy, is the cause instead, and it destabilizes chromosomal patterns.
217) If the suppressor gene mutation may lead to disorders and cancerous cell growth.
218) BRAF gene mutation has been confirmed to be closely related to the dedifferentiation of papillary thyroid carcinoma.
219) AIM To study the sodium nitrite induced DNA mutation by convolution spectrometry ( CS ) .
220) Barring a genetic mutation, the search for noumenal reality is a journey along an asymptotic sinuous trail.
221) This batch of new mutation not only larcenous Zhang date, use what return meeting block local area network normally, still can bring about a system to break down even.
222) For different genetic locations the results of amplification show diversities which result from mutation and recomposition of genomes, so RAPD can identify genomes.
223) The Chinese stock market of recent years was studied, and the results show that the fluctuation of prices in the stock market has the characteristics of durative, mutation and sensitivity.
224) So that is very important , the mutation is very important.
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