1. Intracellular and canalicular cholestasis, as well as periportal ductular proliferation always accompanied these cellular changes as the disease progressed.

2. Conversely, potassium and phosphate are the principal intracellular cations and anions, respectively.

3. However, at high concentrations of intracellular calcium, all calmodulin binding sites are occupied.

4. It is through its regulation of intracellular calcium that InsP 3 functions to regulate so many cellular processes.

5. As indicated previously, intracellular calcium is usually an inhibitor of adenylate cyclase, but this is not invariably the case.

6. Therefore the release of intracellular membrane-bound calcium precedes the onset of the stimulus-induced degranulation.

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7. Glutathione is an important constituent of intracellular protective mechanisms against a number of noxious stimuli including oxidative stress.

8. Mutoh etal showed that intracellular glutathione was mainly responsible for protecting against gastric cell injury induced by ethanol.

9. The mechanism responsible for secretion or intracellular retention of pre-S peptides in chronic hepatitis B virus infection is uncertain.

10. This suggests that platelets must possess very sophisticated intracellular control mechanisms.

11. The reactions may be extracellular or intracellular.

12. METHODS Using conventional intracellular microelectrode recording technique.

13. The sarcoplasmic reticulum is a system of intracellular membranes.

14. Cysteine is the crucial limiting amino acid for intracellular GSH synthesis.

15. Intracellular recording technique of glass microelectrode and technique of intralateroventricular microinjection were used.

16. They are subject to regulation by many neural, hormonal, and paracrine factors, acting via intracellular mediators.

17. The solute concentration in the extracellular space would therefore be much higher than that in the intracellular space.

18. Initial therapy of patients with large tumor masses has been complicated by large releases of intracellular potassium with resultant refractory hyperkalemia.

19. By design, the solute concentration of isotonic saline is the same as that in usual intracellular and extracellular fluid.

20. Histological examination Day 3: The biopsies showed moderate to severe inter and intracellular oedema.

21. Scientific Officer required to assist with a project researching intracellular events in scrapie-infected cells.

22. Legionellae in the enviroment are found as parasites of protozoa in which intracellular multiplication can take place.

23. Magnesium is the fourth most abundant cation in the body and is second only to potassium in intracellular concentration.

24. In this instance, the sodium chloride is entirely excluded from the intracellular compartment.

25. In in vitro preparations of partially purified enzymes, the functional distinction between intracellular and extracellular calcium is lost.

26. Instead, water distribution will be determined by the relative allocation of solute to the extracellular and intracellular spaces.

27. There is indeed direct evidence that mechanical stress can generate intracellular signals that regulate gene expression.

28. Method Cellular proliferation were studied by isotope labeling technique, and the concentrations of intracellular anticancer drugs were measured by fluorospectrophotometry.

29. Bioelectrical impedance analysis(BIA)measures the body composition and its change by the electric feature of the extracellular fluid and intracellular fluid.

30. At highest field strengths, the core of the clot may have low signal on T2-weighted images, due to the presence of intracellular methemoglobin or of deoxyhemoglobin.

31. Extracellular signal - regulated kinase ( ERK ) signaling pathway is a critical signaling pathway that transduce the intracellular signal.

32. Magnetite grains present in the rims of the ALH 84001 carbonates (Fig. 1.1.2.3b) were compared to intracellular magnetite crystals ('magnetosomes') formed by terrestrial magnetotactic bacteria.

33. Total body water, contained principally in blood plasma and in intracellular and interstitial fluids.

34. IMPLICATIONS: A combination of unusual environmental factors may have altered the intracellular skeletal muscle milieu to induce or exacerbate a malignant hyperthermia -like response in this patient.

35. Thus, at highest field strengths, the core of the clot may have low signal, due to the presence of deoxyhemoglobin or of intracellular methemoglobin .

36. Objective : To extract Coriolus versicolor intracellular pepsin inhibitor based on ultrasonic method.

37. Microsporidia are obligate intracellular parasites that can infect a wide variety of animals ranging from insects to human.

38. Thus , the fluorometry was regarded as a suitable method for determining intracellular riboflavin of yeast.

39. The intracellular trehalose metabolism of S . cerevisiae during alcoholic fermentation was studied.

40. Objective To observe the changes in intracellular free calcium ion in salt-sensitive hypertensive rat model and the effects of Antisterone on them, and to search their mechanisms.

41. It may be difficult to rule out hypomagnesemia as the cause of or a contributor to hypocalcemia because the serum magnesium level may be normal, even when intracellular magnesium stores are reduced.

42. The temperature of platelet intracellular ice crystal formation (IIF) is one of the most important physical parameters to instruct platelet cryopreservation.

43. There is an extremely rapid turnover of intracellular fat, with a continuous withdrawal and deposit.

44. Lipids and their metabolites including sphingosine may act as intracellular second messengers which are involved in many biological process.

45. Enzyme - lined results in the modification of an intracellular target protein.

46. A yeast haploid S1(a) with high intracellular content of reduced glutathione (GSH) was selected from 75 yeast strains by primary screening and isolation of haploid, and then marked with auxotroph.

47. The secretion of recombinant protein to periplasm or extracellular medium has more advantages than the expression intracellular as inclusion bodies.

48. The changes of the intracellular concentration of free calcium ion in myocardial cells in each group under different conditions were dynamically measured with spectrofluorometer.

49. A non-intrusive micromanipulation technique, dielectrophoresis, can be used to assist the investigation of intracellular adjustment.

50. Zidovudine may competitively inhibit the intracellular phosphorylation of stavudine. Therefore, use of zidovudine in combination with Stavudine is not recommended.

51. Methods The cultured PC12 cell was treated with oligodendrocyte and its debris respectively, and intracellular concentration of calcium of PC12 cell was detected at different time after treatment.

52. The intracellular calcium level of neurons was measured with flow cytometry.

53. This protective effect of glucose may result from its ability to clear accumulated intracellular Acetyl Coenzyme A and to promote the Production of intracellular energy substances.

54. Human APOBEC3G is a cytidine deaminase that represents one such barrier, conferring broad intracellular antiretroviral protection.

55. Objective To explore the possibility of using HBV as a gene delivery vector, and to test the anti-HBV effects by intracellular expression of antisense RNA.

56. L-type calcium channel played a very important role in intracellular calcium transportation of odontoblast cells and involved in the process of the dentin mineralization.

57. Stimulate collagen synthesis and increase intracellular fluid. Effectively reduce fine lines, lift skin contours, firmness tightness.

58. Objective: To study the intracellular site of biosynthesis of Met-enkephalin (MEK) and its regulation in rat dental pulp tissue.

59. In order to fuse, intracellular vesicles have to move within the cell.

60. The actin cytoskeleton, a dynamic network of intracellular proteinaceous structural elements participates in many physiological activities in plant cell.

61. The balance between intracellular active oxygen production and the defense system might break down in air-dried and dried field samples.

62. We posit that treatment with N-acetylcysteine, a precursor of glutathione, the largest intracellular thiol pool against oxidative stress, could reverse cardiac hypertrophy and fibrosis in HCM.

63. Potent intracellular bactericidal action may be exerted through the myeloperoxidase - hydrogen peroxide - halide bactericidal system.

64. The intracellular concentration of 2,3 DPG , ATP and SOD of erythrocyte were measured.

65. The said physiological multi-salt liquid is used in curing infantile diarrhoea for correcting water and electrolyte disorder of extracellular fluid and intracellular fluid separately.

66. Autophagy stabilizes intracellular environment and maintains cell survival through balancing anabolic metabolism and catabolism.

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67. The emodin - treated HK - 2 cells significantly decreased the H 2 O 2 - induced intracellular ROS level.

68. Intracellular concentration of daunorubicin(DNR)measurement by flow cytometry showed that TMP could elevate the concentration of DNR in HL60/HT cells.

69. Intracellular thiols such as glutathione(GSH), cysteine(Cys), and homocysteine(Hcy) play a crucial role in maintaining biological redox homeostasis.

70. ROS also can serve as intracellular signaling molecules participating in cell growth and cytokine production.

71. The lack of Mg usually cause the lose of intracellular K and influence the oxidative phosphorylation of the cell.

72. The effects of the structures of the compounds on the insect glutamate potentials were investigated by using electrophysiological intracellular microelectrode recording technique.

73. Microsporidia are obligate intracellular parasited eukaryotes. The range of hosts included invertebrate and vertebrate. The microsporidian species parasited mainly fishes and insects.

74. These proteins transduce outside signals to intracellular effectors and play a central role in almost all physiological functions.

75. The analytical solutions concerning intracellular calcium spiral and target wave in the Xenopus laevis oocyte are obtained.

76. Results: The expression of death receptor 5 ( DR5 ) was certificated in U343 , DR5 appeared to be located in intracellular perinuclear compartment.

77. This translates into enhanced therapeutic efficacy for drugs like doxorubicin that hae intracellular site of action.

78. Objective To explore the possibility of using HBV as a gene delivery vector,[] and to test the anti-HBV effects by intracellular expression of dominant negative mutants of core protein.

79. By using living cell imaging, time-lapse monitoring and FRAP technique, the intracellular behavior of poliovirus plus-strand RNA was studied in living host cells.

80. Standard microelectrode intracellular recording technique was used to record action potential(AP) of ventricular papillary muscles.

81. Intracellular PHB depolymerase and 3 hydroxybutyrate dehydrogenase catalyze the initial reactions of intracellular PHB catabolism.

82. Intracellular Ca 2 + fluxes were assessed in fura 2– loaded , oltage - clamped rabbit entricular myocytes.

83. Brucella spp are the facultative intracellular pathogens with the ability to survive and multiply in phagocytes, and they can cause abortion of pregnant domestic animals and undulant fever in humans.

84. Treatment of hepatocytes with clofibrate caused a significant increase in intracellular and mitochondrial ROS.

85. Itwas found that the intracellular primary hypha of the pathogen was developed and deposited by a layer of accidented electron-opaque material after invading host tissue.

86. Over 50% of human cancers have been identified as resulting from just two intracellular signaling pathways: the JAK/STAT and p53/ras pathways.

87. Improved extraction process of intracellular medicine, increased yield and reduced solvent consumption.

88. H-FABP plays an important role in the intracellular transportation of fatty acid, the metabolism of lipids, regulating cell of acute myocardial infarction (AMI).

89. We thought that these phenomena were interrelated to the two different intracellular calcium signaling pathways existed in Flammulina velutepes.

90. They transduce or convert extracellular stimuli into intracellular signals through a number of signaling pathways, including neurotransmitters, light, hormones, lipids, and proteins.

91. Intracellular supply of deoxythymidine triphosphate is a highly regulated process and is important for DNA replication and repair processes.

92. Methods: Combination of the intracellular injection and electron microscope techniques were used.

93. It was found that total intracellular diacylglycerol (DAG) levels were significantly increased in cultured vascular cells exposed to elevated glucose.

94. Myocyte cells of central zone of I/R heart showed intracellular edema, swollen and damaged mitochondria, and fragmentation of cristae and concentrated nucleus.

95. For this study, the Cambridge researchers used advanced fluorescence microscopy techniques to observe intracellular growth of Salmonella bacteria within living cells.

96. ConclusionAssessment of myocardial intracellular TG by 1HMRS ex vivo is feasible and there is positive correlation between the MRS assesment of TG% and cell count.

97. Herpesviruses bud from the nuclear membrane into channels that lead directly to the intracellular space.

98. The automatic activity of aortic vestibule was studied in 82 guinea-pig heart preparations with intracellular microelectrode.

99. Gram-negative diplococcus was found in the samples from 11 (9.2%) Group B mothers. Intracellular Gram-negative diplococcus was also seen.

100. Lipid droplets in cytoplasm were observed by oil red O staining. The contents of intracellular cholesterol ester were detected by enzyme-fluorescence.

101. Whether are the LDSWs able to induce the rapid release of ATP from intracellular plasma?

102. The structure of CB reveals serious injury and intracellular content of monoamine reduces progressively in AIRS.

103. Lysophosphatidic acid ( LPA ) is one of the simplest natural phospholipids. It is an intracellular phospholipid messenger.

104. The intracellular polysaccharides of Agaricus blazei Murill by submerged culture were extracted by enzyme hydrolysis method.

105. The binding stimulates leukocytes and triggers an intracellular cascade of signaling reactions.

106. However, there mat be intracellular genetic alterations such that ontogenetic histories are altered resulting in two different mature forms.

107. We propose that the central nervous system is the critical organ for the coordination of intracellular metabolic processes that are essential to guarantee energy homeostasis at the organismal level.

108. With the TOCP treatment time prolonged, intracellular MDA and CAT levels showed obvious time-effect relationship.

109. Where K1, K2 Klebsiella pneumoniae anti-type neutrophils and phagocytosis and intracellular killing effect against stronger than non-K1, K2 type, therefore, K1, K2-based prevalence of high toxic.

110. OBJECTIVE To investigate the hypolipidemic effects of ferment liquid(GFL) and intracellular polysaccharide purified(GIP) of Grifola frondosa.

111. Objective:To investigate the ultrastructural intracellular distribution of metallothionein (MT) in acute cadmium exposed rat liver, especially in liver parenchymal cells.

112. Calcium stores, endoplasmic reticulum and sarcoplasmic reticulum, play important functions in controlling the level of intracellular calcium.

113. Membranes also provide structural support and act to anchor intracellular structures.

114. In this experiments, buthionine sulfoximine (BSO), a GSH synthase inhibitor used to adjust intracellular GSH content, was observed its radiosensitization effect in vivo and in vitro.

115. It is concluded that acrolein induces adult mice cardiomyocytes apoptosis, and it may be due to the increased intracellular oxygen free radicals and calcium concentration.

116. Acyl-CoA: cholesterol acyltransferase(ACAT) is an intracellular enzyme that catalyzes the formation of cholesterol esters from long-chain fatty acyl coenzyme A and cholesterol.

117. Through the studies on biochemical mechanism, the malolactic conversion mechanism was proposed that MLF was catalysed by LAB intracellular malolactic enzyme (MLE).

118. Measurement of intracellular daunomycin ( DNR ) and membrane glycoprotein ( P - gp ), by flow cytometry.

119. When AMPA receptor is activated, lots of intracellular Ca ~ ( 2 + ) result in neurons injury.

120. AIM: To determine the effect of reactive oxygen species on the baroreflex and to investigate the intracellular mechanism responsible for baroreflex dysfunction in the heart failure state.

121. Insulin stimulates the translocation of glucose transporter 4 (GLUT-4) from intracellular GLUT-4 storage vesicles (GSV) to cell membrane in striated muscles and adipose tissue.

122. The results showed that the intracellular DNA content at prophase or telophase was twice as much as at interphase.

123. Organelle - cell fluorescence intensity ratio analysis was adopted to study the intracellular distribution of HMME.

124. The intracellular concentration of DNR in AML cells was measured through fluorospectrophotometry.

125. MTT and plaque formation test on C6/36 cell showed intracellular immunity to dengue virus.

126. In the same experiment, LMV did not affect the levels of HBV proteins or HBV RNA despite inducing significant reductions in HBV virion production and intracellular HBV DNA replication (Table 3).

127. Cathepsin is a class of intracellular lysosomal proteases and has a close relationship with the fibrosis and tumor development in multiple organs.