1. Point mutations were created by oligonucleotide-mediated site-directed mutagenesis and confirmed by DNA sequencing.

2. Apart from point mutation, another way in which oncogenes can be activated is by over expression.

3. Thus, both of the point mutations characterized here would be expected to eliminate kinase activity of the proposed atk protein product.

4. Result: We had not point mutation in all subjects.

5. Conclusion Abore point mutation is an inherited gene mutation.

6. Conclusion: The point mutation in this area of mitochondrial DNA might not be related hereditary ataxia.

6. try its best to collect and create good sentences.

7. A point mutation is foundin two patients at nucleotide 31119 , resulting in G ( CGA ) to A ( CAA ).

8. Point mutation was produced in the cellular receptor binding region of hepatitis A virus VP1 based on PCR directed mutagenesis.

9. Missense mutation A point mutation that causes a change in one amino acid of a protein.

10. Objective To investigate the point mutation features of exon 11 and 12 in phenylalanine hydroxylase( PAH )gene of the patients with phenylketonuria(PKU)in Xinjiang.

11. Applying RNase Protection assay, the point mutation in the RB gene was observed.

12. The use of immunohistochemical staining as a marker of point mutation has been critically reviewed by Wyndord-Thomas.

13. Loss of tumour suppressor function requires inactivation of both alleles, usually by chromosomal deletion or point mutation, or both.

14. Nineth five percent of large bowel cancers showing loss of heterozygosity for 17p alleles also contain a point mutation.

15. In BCR - fusion gene negative myeloproliferative diseases, the discovery of JAK 2 V 617 F point mutation is an important landmark.

16. Results Among the 130 cases of primary amenorrhea, 33 had abnormal karyotypes. A point mutation at exon 7 of GHRHR gene was found in one patient.

17. Conditional gene knock-out is a new technique set up more than ten years ago. This technique can change intravital genetic information and introduce point mutation into animal body precisely.

18. The mutations in patients with factor V deficiency were identified including point mutation, frameshift mutation, deletion and insertion mutation.

19. Strangely, in a few percent of the offspring of Lolle and Pruitt's mutants, one copy of hothead spontaneously reverted to the normal version, repairing its point mutation.

20. In this article, the growth regulating mechanism of chicken is discussed, The sex-linked dwarfism in chickens is due to the GHR gene mutation and point mutation and deletion are two main forms.