(1) Many cancers rely on collagenase to break down collagen in connective tissues.

(2) Time of incubation in collagenase solution: 60 min.

(3) To investigate the mechanism of collagenase in preventing adhesion of intrathecal tendon.

(4) Conclusion The collagenase with high quantity and activity could be induced in the improved medium.

(5) Collagenase is one kind of enzymes that can degrade native helical collagen fibrils or glutin but not degrade others proteins.

(6) To investigate whether collagenase can cause proteoglycan hydrolization in lumbar nucleus pulposus within the action time.

(7) MethodsPrimary human insulinoma cells were isolated by using collagenase type P, and then purified by repeatedly selective cell culture.

(8) The changes of collagenase and collagenous fiber in the periarticular soft tissues of the animal models and the influence of FHWT on them were observed.

(9) Conclusion:The target-injection of collagenase for intervertebral disk chemolysis may be complementary therapy for recurrent postoperative lumbar disc herniation.

(10) Helps restricts the formation of collagenase, prevent collagen and thus maintain skin's elasticity.

(11) Conclusion Collagenase could prevent adhesion of intrathecal tendon without affecting tendon healing.

(12) ICH models were produced with the induction of collagenase type - S except normal group.

(13) OBJECTIVE To prepare the collagenase immunizing conjugation product for injection.

(14) Conclusions Infusing collagenase andheparin into rat caudate is a convenient and effective method to establish a stable, reliable and duplicable cerebral hemorrhage rat model.

(15) Conclusion: by the use of trypsin and collagenase in digest process and the L polylysine differential adhesion method highly pure Schwann cell can be obtained in short time.

(16) The immunizing conjugation product of collagenase in this program was prepared by EDCI method.

(17) Islets were isolated by collagenase digestion and were transplanted under the left kidney capsule.

(18) Objective To isolate and purify collagenase with high quantity and activity.

(19) OBJECTIVE: To assess the mechanism of epidural injection of collagenase in animal models of lumbar disc degeneration.

(20) AIM:To probe into the related factors that influenced the effect of epidural injection of collagenase in patients with lumbar disc herniation under the observation of X ray.

(21) Objective To investigate the causes of the initial nerve roots lesion after collagenase chemonucleolysis.

(22) This paper reports the successful isolation of islets of Langerhans from the rat pancreas using a modified collagenase digestion, Ficoll density gradient separation and hand-picking technique.

(23) Methods Sheep lumbar intervertebral disk displacement and degeneration 10 weeks before intradiscal injection of collagenase.

(24) Methods: The upper compartments of both TMJs of 8 goats were injected with collagenase to induce osteoarthrosis.

(25) Testes from 18-day-old embryonic chickens were used to isolate seminiferous epithelial cells by sequential two-step enzyme digestion with collagenase and trypsin.

(26) We considered CT number of the disc as an objective index for prognosis of collagenase chemonucleolysis.

(27) According to experience from practice, it is emphasized that main causes of fault is too deep insertion of the perfusion tube end and collagenase dosage is improper.

(28) CONCLUSION:Treatment of skin scar is mainly inhibiting the synthesis of fibroblastic protein and stimulate the synthesis of protease, especially collagenase.

(29) Objective: To investigate the influential factors and clinical therapeutic effect of epidural injection of collagenase for the treatment of cervical intervertebral disc protrusion.

(30) Objective To find the evidence of the effect of microbiotic collagenase in root surface caries by observing the destruction of collagenous matrix on root surface.

(31) Methods: Locating by lumbar vertebrae X-ray, 201 patients with PLID received collagenase injection through lateral angles of canalis vertbralis into epidural cavity.

(32) BACKGROUND: The mechanism of epidural injection of collagenase to treat lumbar disc degeneration is still unclear.

(33) Objective To observe the relationship between morphological mutation of rabbit cornea after cornea alkali burn and the variation of collagenase content in lacrima.

(34) Objective: To observe the effect of treatment of prolapse of lumbar intervertebral disc(PLID) with collagenase injection through lateral angles of canalis vertbralis.

(35) This study is to investigate the antitumor activities of the immunoconjugates composed of anti-type IV collagenase monoclonal antibody 3G11 and lidamycin (LDM) prepared by different methods.

(36) Methods: Using different techniques of collagenase digestion and discontinued density gradient centrifugation adultrat islets were prepared.

(37) Objective : To conclude therapeutic effect of systemic health education on intervertebral disclysis patients by collagenase.