1. Thrombin has the endovascular and extravascular effects.

2. The appearance of serine proteases such as thrombin, tissue plasminogen activator and plasmin in the CNS have come under increasing scrutiny.

3. The ultimate result is the formation of the thrombin and fibrin clot, and each enzymolysis accompaniment magnify effective.

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4. Conclusion Thrombin can lead to brain edema after cerebral hemorrhage which can be restrained by Hirudin. And then, hirudin doesn't produce any negative effect on brain tissue.

5. This vector also contains thrombin protease cleavage site to facilitate proteolysis of the bacterial fusion proteins.

6. Similarly, fluorescent thrombin bound ubiquitously on the surface of fibrin clots, overlapping slightly with PS - exposing platelets.

7. Conclusion Thrombin stimulates HMC to produce ET 1 and ET 1 mediates the HMC proliferation.

8. Snake venom thrombin - like enzymes belong to the fibrinogenolytic enzyme family and are serine proteases.

9. Objective:To study clinical value of radiocystitis therapy with thrombin intra-bladder perfusion.

10. Hirudin is an anticoagulant directly acting on thrombin. Its molecular biological and pharmacological properties, mechanism of action, current clinical researches and uses were reviewed.

11. AIM To investigate the apoptotic effect of thrombin on brain microvascular endothelial cell(BMVEC) of cultured rat, and the protective effect of hirudin, an inhibitor of thrombin.

12. Thrombin in blood is a new haemostatic which is exploited in recent years.

13. PA form, size, neck length and width, thrombin dose, therapic effect and complications were analysed.

14. Objective : To observe thrombin activity in a rat model of aortic endothelial denudation.

15. Conclusion Thrombin lead to brain edema after cerebral hemorrhage that could be restrained by hirudin, and hirudin didn't produce any negative effect on brain tissue.

16. In response to bleeding, a complex series of clotting-factor interactions leads to its conversion by thromboplastin to thrombin, which transforms fibrinogen in plasma into fibrin.

17. When the tissue damage, the release of thromboplastin to prothrombin into thrombin.

18. Conclusion The therapeutic effect of false arteria femoralis by using compression method and injecting thrombin into aneurysm cavity by color doppler ultrasonic guidance is therapeutical and safe.

19. Primary culture of human embryonic hepatocytes was employed to study the effects of catecholamine and thrombin on the secretion of histidine rich glycoprotein(HRG).

20. METHODS: NPE was made with intracisternal injections of fibrinogen and thrombin.

21. Objective To investigate the toxic damage Jn thalamic tissue mused by thrombin and whether can be reversed.

22. Activated partial thromboplastin time (APIT), prothrombin time (PT) and thrombin time (TT) were evaluated by test tube method using rabbit named New Zealand White.

23. The changes of pro and posthemodialysis in platelet counting, thrombin time and activated partial thromboplastin time were investigated.

24. Conclusion Damage to the thalamic tissue might be caused by thrombin and reversed by hirudin.

25. The results also showed that the inhibition of plasmic thrombin formation in various dosage groups was positively correlate with the injected dose.

26. Objective : To evaluate the hemostatic efficacy and safety of a human thrombin in tonsillectomy.

27. Next, the researchers pitted the dragon's blood compounds in test tubes against two foes: ulcer-causing H. pylori bacteria and thrombin, a blood-clotting agent.

28. Objective:To explore clinical significance of detecting prothrombin time(PT), the activated partial thromboplastin time(APTT), thrombin time(TT), plasma fibrinogen(FIB) for parturient women.

29. PurposeTo calibrate the 2 nd national standard for human thrombin by the collaborative study.

30. Objective To explore the clinical significance of platelet, prothrombin time , activated partial thromboplastin time , thrombin time , plasma fibrinogen for parturient women.

31. Result The thrombin time was distinctly shortened ( P 0.01 ) after the ions joining into the extraction.

32. Objective : To evaluate the effect of thrombin in endothelial cell permeability.

33. Purpose : The study was designed to evaluate the therapeutic efficacy of ultrasound - guided thrombin injection for catheterization.

34. The blood coagulative system in three groups was evaluated by testing platelet count (PLC), Active part thrombin time (APTT), prothrombin time (PT), thrombin time (TT), FIBrinogen(FIB).

35. A plasma protein that is converted into thrombin during blood clotting.

36. The article reviews the general characteristics of thrombin and its neurotoxic effects.

37. Thrombin was further purified with CM ion - exchange liquid chromatographic column.

38. Objective:To study the effects of combination of quercetin monosulfate and 5' chloro 5' deoxyadenosine on platelet aggregation induced by thrombin in rabbits.

39. FG is prepared from platelet - rich plasma or by mixing concentrated fibrinogen solutions with thrombin.

40. Factor X is activated(http://), which combines then with factor V to generate thrombin.

41. Conclusion:The kinetic measurement for thrombin generation could become a new trend for coagulative function evaluation because of its utility and feasibility.

42. Objective To investigate the mechanism of brain injury caused by thrombin and the intervention effect of hirudin and nimodipine.

43. A large amount of thrombin produced in hematoma and its surrounding tissues after intracerebral hemorrhage.