1. To study the isoniazid acetylator Phenotype.

2. Isoniazid may cause severe and sometimes fatal liver damage.

3. Isoniazid comes as a tablet and a syrup to take by mouth.

4. method for determination of the plasma concentrations of isoniazid ( INH ) and its metabolite acetyl - isoniazid ( AcINH ).

5. All of four aromatic amines inhibited acetylation of isoniazid, but amides did not. 4-Aminobenzoic acid can be considered as a combined-drug for increasing and prolonging the blood level of isoniazid.

6. The drug isoniazid is widely used in the treatment of tuberculosis.

7. A rapid qualitative of isoniazid in serum by tandem mass spectrometry is reported.

8. The duration of triple chemotherapy with isoniazid, rifampin, and ethambutol , disease severity, operative procedures, and outcome were analyzed.

9. However , if isoniazid causes an upset stomach, it may be taken with food.

10. The most common anti-TB medicines are isoniazid, rifampicin, pyrazinamide and ethambutol.

11. To observe the clinical effect of injecting rifampicin, isoniazid and dexamethasone into pleural cavity on tuberculous pleurisy.

12. Each cases was conducted the patch test of Isoniazid, Rifampicin, Pyrazinamide, Ethambutol streptomycin.

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13. To investigate the relationship between isoniazid - resistance and Kat G gene mutation or deletion.

14. Results Ethambutol hydrochloride, isoniazid, pyrazinamide and rifampicin all had good chromatographic behavior.

15. Objective : To establish a HPLC method for determining rifampicin and isoniazid in human plasma.

16. First-line treatment for TB consists of a pill of each of four antibiotics — isoniazid, rifampicin, pyrazinamide and ethambutol — taken every day.

17. Multidrug-resistant TB (MDR-TB) is a form of TB that does not respond to the standard six month regimen using first line-drugs (i.e. resistant to isoniazid and rifampicin).

18. Objective:To establish a method for determination of assay of Rifampin, Isoniazid, and Pyrazinamide Capsules and Tablets.

19. Conclusion: The method can be employed to determine VB _ 6 in compound isoniazid tablets.

20. Objective To study the application of gene chip in detecting Mycobacterium tuberculosis resistant to rifampin and isoniazid.

21. The prospective pilot study enrolled 24 patients with tuberculosis who underwent FDG-PET scans prior to receiving treatment with isoniazid, rifampicin(), and ethambutol.

22. To establish a HPLC method for determination of the plasma concentrations of isoniazid ( INH ) and its metabolite acetyl - isoniazid ( AcINH ).

23. Aim To establish a methods for the determination of isoniazid tablets by UV.

24. Conclusion The L-forms were formed spontaneously or induced by rifampin, isoniazid and ethambutol .

25. Methods To measure the drug resistance of the separated bacterial strains to the 4 kinds of anti-tuberculosis drugs including streptomycin (SM), isoniazid(INH), rifampicin(RFP)and ethambutol(EMB).

26. According to the view point of drug metabolic regulation, the effects of six aromatic amines and amides on isoniazid acetylated metabolism were studied in rabbits.

27. Objective To examine of optimum condition to detect the resistance genes of rifampin and isoniazid in Mycobacterium tuberculosis by using coloration gene chips.

28. Results L-form of M. tuberculosis was induced by the concentrations of routine inhibition test of rifampin, isoniazid or ethambutol.

29. Aim To observe the hepatotoxic effects induced by Rifampicin (RFP) and Isoniazid (INH) when used alone or in combination on mice.

30. These medications include anabolic steroids, lithium, anti-tuberculosis drugs rifampin and isoniazid, anti-epileptic drugs and medications that contain iodine .