1, Severe nuclear damage indicated by pyknosis and karyolysis are customarily taken as evidence of cell necrosis.

2, Objective: To explore the clinical characters of pyknosis insufficiency of ventricular myocardium with viral myocarditis.

3, It could be found there were pyknosis of neuron, depolymerization of ribosome, accumulation of lipid droplets and lipofuscin, condensation of chromatin.

4, Result: Pyknosis insufficiency of ventricular myocardium tended to appear with viral myocarditis.

5, Results: For the neuron, we can find pyknosis of neuron, depolymerization of ribosome, accumulation of lipid droplets and lipofuscin, condensation of chromatin.

6, The major lesions included dissolution of Nissl bodies, pyknosis, and incrustation of neuronal surface in the cerebral cortex, thalamus, hippocampus, cerebellum and spinal cord.

7, Conclusion Cells of rabbit SAN are decreasing with ageing and there is pyknosis and nuclei splitting in old group.

8, In 3-month-course group, all the changes above appeared to be more serious with capillarectasia, basement membrane thickened,[http:///pyknosis.html] rod-cell nucleus pyknosis and metachromatin condensed.

9, Results The Nissl bodies in the spinal cord and the DRG neurons were observed to have pyknosis, accompanied by collapse and karyolysis of Nissl body.

10, The cell organs were increased in density, and myofibrilla were pyknosis or necrosis, the mitochondrial cristae were decreased. The lysosome and cardionatrin granule were enhanced.

11, The senescent chondrocytes were distributed in the central zone where apoptotic morphological characteristics obviously appeared, such as pyknosis, karyorrhexis.

12, RESULTS: PDT resulted in condensation of mitochondria, reduction of rough endoplasmic reticulum, dilation of smooth endoplasmic reticulum, breakup of nuclear membrane and pyknosis of nucleolus .