1. Sugar, however, blocked the release of orexin.

2. Mutations in the orexin receptors are associated with narcolepsy, a chronic sleep disorder.

3. Glucose can block brain cell secretion of orexin, which keeps us alert. But amino acids can stop that block. Christie Nicholson reports.

4. "Orexin sets the tone," Renger says, that enables those brain changes to occur.

5. When orexin was injected into the brains of mice, the animals stayed awake longer and levels of amyloid beta in their brains increased.

6. A drug that blocked the action of orexin led to a significant reduction in levels and increased the amount of sleep.

7. Johnson's research results suggest that orexin plays a role in the pathophysiology of panic attacks and that orexin antagonists may someday be one means of treating panic disorder.

8. Orexin comes in tiny doses, but it has a profound effect.

9. Scientists marked orexin cells in mice brains so they would fluoresce.

10. In laboratory trials of some experimental agents, an orexin antagonist proved anxiolytic and attenuated panic attacks in rats challenged by sodium lactate, a standard agent for inducing panic.

11. Scientists marked orexin cells in mice brains so they would fluoresce. Then they tracked the cells' activity after feeding the mice different kinds of food.

12. Objective In order to explore the role of orexin A, B in appetite regulation of diet-induced obesity resistant (DIO-R) rats.

13. "Orexin is produced in only one part of the brain, the dorsomedial-perifornical hypothalamus, " said Johnson.

14. Neurons there with high levels of orexin play a critical role in key factors in panic, like arousal, vigilance, and mobilization of the central autonomic system.

15. The scientists also found a link with orexin, a protein involved in regulating the sleep cycle.

16. High fat diets increased the content of orexin A and orexin B of rats, but there was no significant difference between DIO-R and DIO rats.

17. Sugar can increase energy, but in very small amounts, sugar can tell your brain to degrade the performance of orexin.

18. Furthermore, blue light via an optical fiber precisely and reliably generated waves of spikes in the orexin cells.http://

19. A mixture similar to the protein content of egg whites activated these cells, triggering the release of the stimulant orexin.

20. Turns out that glucose blocks the function of the orexin cells. This effect might be the main reason for the desired post-lunch siesta.