1. The pharmacokinetic results showed that the perilymph AUC of intratympanic injection(it) DSP-loaded gel was 492.8-fold higher than that of iv DSP solution.

2. To seek evidence for perilymph cerebrospinal fluid barrier ( CSF ).

3. It'should be differentiated among endolymphatic hydrops , perilymph fistula , mumps deafness , and otitis media with effusion.

4. The experimental animal model of perilymphatic fistula (PLF) was made by drilling a small hole in the skull and injecting artificial perilymph into the subarachnoid space in 50 Guinea pigs.

5. Variations in round window membrane permeability and in perilymph flow could account for why hearing losses are observed in some patients.

6. Results The artificial perilymph did not induce a change of the amplitude of CM and I/O function.

7. Conclusion: The sensibility of the method is high, accurate, and repeatable. It can be used to determine the content of dexamethasone sodium phosphate in perilymph.

8. Peak concentrations and gradients for gentamicin varied considerably between animals, likely resulting from variations in round window membrane permeability and rates of perilymph flow.

9. OBJECTIVE To establish a method for determining the concentration of dexamethasone phosphate in the perilymph of guinea pig.

10. Objective To observe the effect of noise on the concentration of glutamate in perilymph and cochlear potential of guinea pig cochlear.

10. try its best to gather and build good sentences.

11. Results After topical administration or intracardial injection of DEX, concentrations of drug in perilymph and plasma decreased gradually over time.

12. By the GM pharmacokinetic analysis, it suggested that the accumulation of drugs in perilymph be a key point of GM ototoxicity by the disturbance of the blood-labyrinth barrier.