1. Ligand is seeking another collaboration to develop diabetes drugs.

2. No obvious regional differences in response to ligand were detected in these cultures.

3. Ligand is also conducting phase three trials on Targretin for a form of lymphoma and is looking at it for other cancers.

4. Ligand binding to the EGF receptor therefore seems to be integrally associated with liver cell proliferation.

5. Similarly, one involving transfer from ligand to metal is called a reductive charge-transfer transition.

6. Ethylenediamine tetra Methylenephosphonic acid is a new multidentate ligand.

7. The binding mode of the ligand was completely preserved when the complex was prepared with the ligand.

8. Chiral amino alcohol is a kind of the ligand or catalyst with great potential for the development of catalytic asymmetric synthesis.

9. Conclusion: Fas and its ligand could play a an role in the injury of human glomerular cell.

10. The result showed that ligand has good coordination ability with rare earth ions, and a binuclear complex was formed.

11. A proliferation-induced ligand(APRIL)is a recently found member of tumor necrosis factor (TNF)superfamily.

12. That is specifically activated by an artificial ligand called a chemical inducer of dimerization.

13. It was found that the ligand and complex of polymers are thermotropic nematic liquid crystals with wide mesomorphic temperature range.

14. The results corroborate the role of these proteins in pheromone transport and elaborate the structural basis of ligand binding.

15. Calcium will interfere and is eliminated by complexing with a ligand which binds calcium and not magnesium.

16. There are no main-chain hydrogen bonds to the metal ligand side chains.

17. Confirmation of this adaptation of the V-domain interface in cell-adhesion interactions now awaits direct structural data for the ligand or the complex.

18. Moreover , there is a chiral quaternary carbon in the 1 - hydroxyethylidenediphosphonic ( hedp ) ligand.

19. The synergic extraction is main to from multicomponent complex of mixed ligand in extractive separation.

20. Molecu lar docking serves as a method to simulate the interactions of two molecules (such as ligand and receptor) and to predict their binding mode a nd affinity.

21. During these initial studies, none of the side effects associated with the anti - ligand antibodies were observed.

22. In this paper, the recent application status of micellar mixed ligand complexes in spectrophotometry are reviewed.

23. Backbone and side chain flexibility can either decrease or increase upon ligand binding.http:///ligand.html

24. There is 35% homology between the amino acid residue of the Ang and RNase and their similar spatial structure can both combine with RI as ligand.

25. Molecular recognition has stimulated an explosion of solid phase ligand designs and affinity chromatographic applications.

26. This article dissert on pyrazine derivant of natural presence, spice with structure exchange some regularity and in food flavour of ligand model.

27. MethodsThe supporter paper fiber was activated with epoxy chloropropane etc. According to the influence of spacer and different ligand on absorption of kinase, process route was optimized.

28. Urethane has a wide spectrum of effects and affects both inhibitory and excitatory ligand - gated channels.

29. A series of photosensitizers of ferrum complex with dialkyl dithiocarbamic acid as ligand is synthesized, their infrared and ultraviolet spectra are tested.

30. Methods The supporter paper fiber was activated with epoxy chloropropane etc. Accordiag to the influence of spacer and different ligand on absorption of kinase, process route was optimized.

31. The coordinate bond property, ligand field intensity and the stability of coordinate complex which nitrite and nitro group as ligand were discussed in this paper.

32. Magnesium is essential for PTH secretion and activation of the PTH receptor ligand.

33. The present invention relates to 1, 2- substitute cyclopentadienyl ruthenium surface chiral ligand in the chemical field and the correspondence synthetic method.

34. And if there is a hydroxyl in ortho position of carboxyl, the oxygen of hydroxyl and carboxyl in ligand are bound to Ti to form hexatomic cyclic compound.

35. A simple method of calculating the acidity existing scope when determining the ligand concentration via ternary coordination compound was presented in the paper.

36. The invention discloses chiral diphosphine ligand, the synthesis method and application thereof.

37. Ligand exchange chromatography with chiral mobile phases was established for the separation of theanine enantiomers.

38. Mixed-mode chromatography is a new kind of chromatography technology for bioseparation. The special ligand combines two or more interaction modes, commonly hydrophobic and electrostatic interactions.

39. It make the biomacromolecule separated mainly according to the affinity between the biomacromolecule and immobilized ligand.

40. Addition of the second ligand will enhance the luminescence, too.

41. The formation of intramolecular hydrogen bonding extends the ligand planarity and increases the insertion ability of the complex to DNA.

42. To explore the effects of CD 40 - CD 40 ligand ( CD 40 L ) interaction on endothelial cells ( ECs ) procoagulant activity.

43. Conclusion: S-alkyl-L-cysteine as the binding ligand can be applied to affinity chromatography for alliinase purification.

44. Using o-phenylenediamine and iminodiacetic acid to synthesize ligand bis (2-benzimidazolyl methyl) amine (L7); 3.

45. The first part reviews the history and recent developments of porous metal-organic framework materials and hydrazone ligand of metal complexes, and clarify the significance of their research.

46. MICB is a stress-induced ligand of the natural killer cell activating receptor NKG2D and is critical for the NK cell killing of virus-infected cells and tumor cells.

47. The addition of the donor ligand such as 4-phenylpyridine N-oxide (PPNO) or trimethylamine N-oxide (MNO) exhibits a minor positive effect on the enantioselectivity.

48. Particle electrophoretic mobility (PEM) changes are shown to correlate well with the amount of ligand fixed on the particles, as probed by its biological activity.

49. Ligand molecules play vitally important roles in the syntheses and surface functionalization of nanocrystals.

50. It was found that the adhesion force between the spheres and the chip surface was affected by the ligand surface concentration.

51. This problem may be conveniently resolved by placing an " arm " between the matrix and ligand.

52. The potency of capsaicin as an immuno- active ligand together with its cytotoxic effects and the induction of a specific immune response could make it an attractive candidate for cancer immunotherapy.

53. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a member of the tumor necrosis factor (TNF) superfamily .

54. AIM : To explore the effects of CD 40 - CD 40 ligand ( CD 40 L ) interaction on endothelial cells ( ECs ) procoagulant activity.

55. In this work(http://), the chromone derivatives that have high anticancer activity and low toxicity to normal cells are used as ligand to synthesize the metal complexes.

56. A new imidazole-dicarboxylate ligand 2-methyl-1H-imidazole-4,5-dicarboxylic acid(L) was purposely synthesized by condensation and oxidation reactions based on o-phenylenediamine and malonic acid.

57. When the complex of anhydrous zinc acetate with 1,5-naphthalene diamine was formed, the anhydrous zinc acetate changed from a bidentate ligand to a unidentate ligand.

58. Ligand 3 b gave higher enantioselectivity ( up to 96 % ee ) and chemical yield.

59. Binaphthol has greatly success in catalyzing of asymmetry reaction as catalyst ligand, which is a research hotspot to organic chemists.

60. Because of its unique properties, dicyanamide ligand coordination complexes play an important role in the field of magnetic chemsitry.

61. With certain caveats, changes in flexibility that occur upon ligand binding, mutation, or changes in sample conditions can be interpreted in terms of contributions to conformational entropy.

62. The bidentate phenyl phosphine ligands which had good electron delocalization and chelation acted as a better ligand than monodentate phosphine ligand.

63. Especially, the ionic iridium complex of the phosphine oxazoline ligand obtains excellent reactional activity and enantioselectivity in the asymmetric hydrogenation of imine and olefin.

64. Second, using Ligand Field Theory accounted for the bleaching mechanism of ART and other tanning agent's.

65. Metal-Organic coordination polymer is formed by self-assembly through coordination bond between bidentate or multbentate organic ligand and central metal ion .

66. Tertiary phosphine ligands are sensitive to air and moisture. Thus we synthesized two stable ligands: the bidentate ON ligand and tridentate ONO ligand.

67. A tetraaza macrocyclic polyamine ligand and its Cu(II) complex were synthesized and characterized.

68. Taking sepharose 4B as carrier, cyanuric chloride as activation reagent, and Erythrina trypsin inhibitor as ligand, the method of preparation of affinity chromatography resin is described.

69. Ligand - receptor binding ( LRB ) is the initial step of signal transduction in cells.

70. The preparing conditions were discussed on mixed ligand complexes of rare earths with L-tyrosine and glycine. Mass spectra of two complexes were analysed.

71. The invention relates to novel water-soluble cellulose derivatives comprising a ligand capable of forming a complex with a polyvalent metal ion.

72. Objective To investigate the relationship between the expression of mannose ligand receptor(MR) and the physiological state of human spermatozoa in fertilization.

73. Macromolecules cannot approach the ligand owing to steric hindrance of the matrix.

74. Objective To investigate potential mechanisms by which CD40 - CD40 ligand (CD40L, CD154) interaction may be involved in the pathogenesis of immunodeficiency and renal injury in haemodialysis patients.

75. An organic chrome crosslinking agent of weak gel for deep profile control has been synthesized by using a monose compound as ligand based on its complexing constant of the complexing agent.

76. It is occasionally necessary to use a number system to designate the position of each ligand.

77. H atom of phenolic hydroxyl in the ligand was attractive to N atom forming intramolecular hydrogen bond, and a new six-membered ring was formed by the hydrogen bond connection.

78. FCM can display soundly the characteristic of the receptor ligand combination between ASGPR and FITC NGA.

79. Nuclear magnetic resonance (NMR) is now a very important approach to study the interaction between small ligand and biomolecule.

80. Ligand for transferrin receptor is the serum iron transport protein, transferrin.

81. The number and affinity coefficient of AGE receptors in peritoneal macrophages of rats supplemented with VC and VE for 5w were investigated using radiolabeled ligand binding experiments.

82. On account of co-metallomicelle formation, the complex with a long alkanol ligand has a stronger catalytic effect than that with a short alkanol ligand .

83. We reviewed the structure and expression of CD40 and its ligand, focusing on the function of CD40-CD40L in regulating immune responses of thyroid associated ophthalmopathy .

83. Wish you can benefit from our online sentence dictionary and make progress every day!

84. Two different methods for recycling ligand were tried in AD and AA reactions, respectively.

85. A possible growth process of ligand(TEPA)-assisted gradual crystallization and subsequent self-assembling is proposed as a plausible interpretation for the formation of those observed structures.

86. Objective To investigate the pathophysiological role of the cardiac adrenomedullin (AM) system, including the ligand and amidating activity in the hypertrophied heart in severe hypertension.

87. For homotopic interaction, the saturation curve, molecular conformation vs ligand curve and certain correlation functions etc. are obtained by means of pure matrix algebra.

88. These reactions involve electrondonation from the incoming ligand to the empty d - orbitals of the molybdenum.

89. Previous studies showed agmatine receptor ligand , prevents morphine dependence, but the mechanism remains unclear.

90. The formation characteristics and conditionsof micellar mixed ligand complexes are also reported.

91. It can hydrolysis glucuronide glycoside bond, releasing the glucuronic acid and ligand.

92. The structure of ligand strongly influenced the kinetics of the ATRP. The fastest polymerization rate and the highest double bond conversion were observed when TEDETA was used as the ligand.

93. It is a main approach for obtaining rare earth metal-polymer complex with high performance to prepare linkage-type complex and incorporate small molecular ligand .

94. The results showed that L was a tetradentate ligand in the formation of the complexes.

95. Radiolabelled glucose, amino acid and ligand are commonly used as PET tracer in meningioma diagnosis.

96. The effects of tridentate ligand structure, central atom, co catalyst and supported on property of catalysts are presented.

97. Agmatine formed by the decarboxylation of L-Arginine by the enzyme L-arginine decarboxylase, has been postulated to be an endogenous ligand for imidazoline receptors (I-R).

98. The synthesis, IR spectrum properties, crystal structure and quantum chemistry of multidentate ligand tris(2benzimidazylmethyl)amine (NTBH2O) are reported in this paper.

99. These reactions involve electrondonation from the inconing ligand to the empty d - orbitals of the molybdenum.