单词 | Crohn's disease |
例句 | 1) Crohn's disease is often associated with iron deficiency anaemia. 2) In Crohn's disease, the activity was mild in 15, moderate in 11, and severe in six patients. 3) Even concordant Crohn's disease twins affected by the disease usually showed very dissimilar subclass ratios. 4) The potential complication impairment of growth in Crohn's disease is unique to pediatric patients. 5) Four patients with clinically active Crohn's disease of the terminal ileum were also studied. 6) Recent studies of resection specimens from patients with Crohn's disease have shown inflammatory microvascular occlusion,(http:///crohn's disease.html) apparently secondary to mesenteric vasculitis. 7) Six Crohn's disease cultures and a single non-inflammatory bowel disease control were positive for M paratuberculosis. 8) The diagnosis of Crohn's disease was made by colonoscopy with biopsy or characteristic radiological appearances on barium studies. 9) It is well known the Crohn's disease is a diffuse lesion of the entire gastrointestinal tract. 10) One hundred and twenty ulcerative colitis patients, 105 Crohn's disease patients and 49 controls were studied. 11) An association between myasthenia gravis and Crohn's disease has been reported previously in only one patient. 12) Forty four patients with Crohn's disease were examined for eligibility during the trial period. 13) In support of this theory there is evidence of a close correlation between activity of Crohn's disease and conditions within the intestinal lumen. 14) Six prospective randomised trials have evaluated the efficacy of elemental diets in Crohn's disease. 15) Twenty two patients were newly diagnosed and 20 were patients with known Crohn's disease in relapse. 16) Growth failure is a major problem affecting up to 50% of children with Crohn's disease. 17) Several studies have shown the efficacy of 6-mercaptopurine and azathioprine in the treatment of both ulcerative colitis and Crohn's disease. 18) Two previous reports have assessed plasma polyunsaturated fatty acid pattern in patients with Crohn's disease. 19) Several reports have quoted numbers of affected and unaffected relatives of Crohn's disease patients, including twins. 20) Lyso platelet activating factor and alkyl acyl glycerophosphocholine were not significantly higher in Crohn's disease than in controls. 21) Peptides, less antigenic substrates than whole protein, are effective in inducing remission in Crohn's disease. 22) Another patient had severe inflammation and numerous granulomata on histological examination of duodenal biopsies indicating Crohn's disease of the duodenum. 23) The authors believed that their serological results supported the view that infection with M paratuberculosis might cause Crohn's disease. 24) The inflammatory cells were absent in the colonic mucosa of Crohn's disease patients examined in remission. 25) Serum concentration of interleukin-6 are also raised in active Crohn's disease but surprisingly not in ulcerative colitis. 26) In another trial this type of diet was as effective as an elemental diet in inducing remission in active Crohn's disease. 27) The role of surgery as a means of improving growth in childhood Crohn's disease is controversial. 28) Activated macrophages are prominent in the inflammatory infiltrate in both ulcerative colitis and Crohn's disease. 29) Thus, there is some suggestion of variation in the immune response within Crohn's disease. 30) Four prospective randomised trials have investigated the role of polymeric formulas in Crohn's disease. 31) Thus a considerable number of cases of both ulcerative colitis and Crohn's disease are sporadic or non-genetic. 32) These data confirm the frequency of growth impairment in childhood Crohn's Disease. 33) There is now substantial evidence that vascular disruption and focal thrombosis, related to macrophage infiltration, occurs in Crohn's disease. 34) The other IgG subclasses were not correlated at the cellular level in either ulcerative colitis or Crohn's disease twins. 35) The overall probability for a patient with Crohn's disease being homozygous for the major locus for Crohn's disease was 0.07. 36) A positive reaction was seen in the bowel wall(), both in patients with Crohn's disease and in controls. 37) Granulomata themselves were comparatively infrequent, and other histological features characteristic of Crohn's disease were less conspicuous than usual. 38) All these parameters were normal in patients with Crohn's disease in remission and in controls. 39) Noeterminal ileal recurrence in those with inactive Crohn's disease was graded endoscopically. 40) A progressive reduction in tissue perfusion may accompany recurrence of Crohn's disease while at a subclinical stage. 41) In clinical trials of Crohn's disease, objective criteria of gut inflammation are desirable, particularly if quantifiable. 42) Kirschner etal, on the other hand, showed low serum IGF-I concentrations in children with Crohn's disease. 43) The importance of early recognition of Crohn's disease before it has such an adverse impact on linear growth is highlighted. 44) Originally only four patients were classified as having definite Crohn's disease and 15 as indeterminate colitis leaving 62 with ulcerative colitis. 45) She had a past history of Crohn's disease which was quiescent and she was taking oral contraceptives. 46) The biopsy from one of the nine healthy Crohn's disease twins turned out to be inadequate for immunohistochemical evaluation. 47) There have been few community based studies of mortality in Crohn's disease. 48) Ulcerative colitis and Crohn's disease are chronic, remitting and relapsing mucosal disorders, collectively known as inflammatory bowel disease. 49) There continues to be no generally accepted indicator of disease activity in Crohn's disease. 50) Seven patients with definite Crohn's disease, seven with indeterminate colitis and 52 with typical ulcerative colitis have a functioning pouch. 51) Only 14 out of 105 Crohn's disease patients showed perinuclear antineutrophil cytoplasmic antibody reactivity by indirect immunofluorescence assay. 52) Crohn's disease is commonly associated with undernutrition, which is often most evident when the disease is active. 53) Before either ulcerative colitis or Crohn's disease was diagnosed infectious and neoplastic diseases had to be ruled out. 54) The role of specific acetyltransferase activity in Crohn's disease patients has not been so far studied, and deserves investigation. 55) Inevitably patients with Crohn's disease or indeterminate colitis will from time to time have restorative proctocolectomy. 56) The poorer prognosis for linear growth among boys who develop Crohn's disease before puberty has not been previously reported. 57) The antibodies were tested in specimens obtained at bowel resection from patients with Crohn's disease and controls. 58) Discussion Our patient had Crohn's disease: the macroscopic and histological features of the oral and perianal lesions are typical. 59) Crohn's disease causes chronic gastrointestinal symptoms which may require prolonged medication and surgical intervention. 60) Despite some similarities, it seems increasingly likely that the pathogenic mechanisms of ulcerative colitis and Crohn's disease are distinct. 61) Salicylate sensitivity A man had small bowel Crohn's disease with multiple strictures diagnosed in 1976 at age 18 years. 62) Elemental diet has been shown to be as beneficial as corticosteroid treatment in children with Crohn's disease. 63) There are conflicting reports of spontaneous and stimulated growth hormone secretion in childhood Crohn's disease. 64) Discussion One of the most distressing aspects for children with Crohn's disease is the effect on growth. 65) So far two of 10 patients with a diagnosis of Crohn's disease have already developed recurrence in the small intestine. 66) Both are considered by some as the most reliable markers of disease activity in Crohn's disease. 67) The difficulty in distinguishing between hypotheses was not surprising since only 209 families with Crohn's disease were available for analysis. 68) Childhood Crohn's disease is often complicated by retardation of linear growth and pubertal development. 69) Methods Patients with active Crohn's disease requiring hospital admission were considered for entry into the study. 70) The study included pairs of twins both concordant and discordant with regard to ulcerative colitis or Crohn's disease. 71) Systemic endotoxaemia has been demonstrated in ulcerative colitis and Crohn's disease and correlates with the extent and activity of disease. 72) Epithelial and lamina propria mononuclear cells were isolated from surgical specimens from control, Crohn's disease,() and ulcerative colitis patients. 73) The diagnostic criteria for ulcerative colitis and Crohn's disease in the probands have been described. 74) Five of the 26 Crohn's disease patients underwent a flexible sigmoidoscopy after four weeks of 1 mg/kg/day prednisolone therapy. 75) A Common Genetic Fingerprint in Leprosy and Crohn's Disease? 76) Clinical trials are under way in the U.S. and Europe testing Trichuris Suis Ova (TSO)—-a species of pig whipworm—as a treatment for peanut allergies, ulcerative colitis, Crohn's disease and MS. 77) "The association was probably most pronounced in terms of Crohn's disease, a subgroup, " Margolis said. 78) Modern-day squat evangelists make money off the claim that a "more natural" posture wards off all sorts of health problems, from Crohn's disease to colon cancer. 79) Calcium deficiency can be found in people with malabsorption problems, such as Crohn's disease, celiac disease, and surgical intestinal resection. 80) Several other illnesses, including Crohn's disease and some cancers, have been linked to imbalances in the species of bacteria that live in our guts. 81) Objective : To investigate the role of arachidonic acid metabolism in Crohn's disease complicated by intestinal fistula. 82) It has even been suggested that gut bacteria has a role in Crohn's disease and autism. 83) However, the primary cause of Crohn's disease is thought to be a dysregulated immune response to gut bacteria. 84) Other autoimmune diseases, such as multiple sclerosis, psoriasis, and Crohn's disease, in parents and siblings were not significantly associated with autism spectrum disorders in the study children. 85) Infliximab, a chimeric IgG1 kappa monoclonal antibody against TNF-alpha, has been effective in the treatment of enteric as well as fistulous complications of Crohn's disease. 86) Crohn's disease (CD) is a chronic transmural inflammatory disease that may involve any part of the alimentary tract from mouth to anus. 87) Inflammatory bowel disease(IBD) includes ulcerative colitis(UC) and Crohn's disease(CD). The pathophysiology mechanisms of the disease remains elusive. 88) Gastrointestinal disorders, such as inflammatory bowel disease and Crohn's disease. 89) Despite these limitations, the development of anticytokine therapies as part of the physician's armamentarium is an important staging post on the road to a cure for Crohn's disease. 90) This finding does not support a significant role for Mycobacterium avium subspecies paratuberculosis in the pathogenesis of Crohn's disease in the majority of patients. 91) Background The comparative efficacy and safety of infliximab and azathioprine therapy alone or in combination for Crohn's disease are unknown. 92) Celiac patients develop an inflammation of the small bowel in reaction to gluten, whereas there is no specific known autoantigen for Crohn's disease. 93) Inflammatory bowel disease such as ulcerative colitis and Crohn's disease may occur here. 94) Background: Intestinal stenosis is a frequent complication of Crohn's disease, often leading to repeated bowel obstruction and surgery. 95) The introduction of the first anti-TNF drug, infliximab (Remicade), revolutionized the treatment of Crohn's disease, wrote Dr. 96) Capsule endoscopy versus enteroclysis in the detection of small-bowel involvement in Crohn's disease: a prospective trial. 97) The richest targets were Crohn's disease and type I diabetes, with nine and seven near - certainties respectively. 98) Rook said that other researchers have used the hygiene hypothesis to show that parasitic infections can aid in the treatment of such conditions as multiple sclerosis and Crohn's disease. 99) Eventually, the research might also help people with Crohn's Disease, Irritable Bowel Syndrome and other gastrointestinal problems. 100) Malabsorption can be caused by infection, surgery, certain drugs, heavy alcohol use, and digestive disorders such as celiac sprue and Crohn's disease. 101) In addition, stomach surgery (gastrectomy), weight-loss surgery and conditions such as Crohn's disease, celiac disease and Cushing's disease can affect your body's ability to absorb calcium. 102) In the present case, we demonstrated that percutaneous drainage of intra-abdominal abscess of Crohn's disease can be a safe and effective measure. 103) Having an intestinal disorder that affects the absorption of nutrients in your small intestine — such as Crohn's disease and celiac disease — puts you at risk of anemia. 104) There's also not enough data to recommend probiotics to kids for constipation, irritable bowel syndrome or Crohn's disease, or to prevent asthma or eczema in children, the AAP reports. 105) We need research to see if the antibiotic that can kill mycobacterium paratuberculosis that may be the cause of Crohn's disease, will also help control ankylosing spondylitis. 106) In the case of Crohn's disease, for example, it will target overactive immune system cells in the gut. |
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