1. A specific leukotriene receptor antagonist awaits development.

2. Dexamethasone has also been reported to suppress leukotriene activity invitro although we found no effect of low dose prednisolone in this study.

3. Establishment of a causal role for leukotrienes in the pathogenesis of mucosal damage has, however, remained elusive.

4. This leads to an excessive production of leukotriene inflammatory chemicals in the blood.

4.

5. New anti-inflammatory tablet-form medication for asthma includes the leukotriene receptor antagonists.

6. Inhibitor of leukotriene A4 hydrolase and of enkephalin degradation in cell preparations from brain.

7. Montelukast, A Selective Cysteinyl Leukotriene Receptor 1 Antagonist, Reduces Cerulein-Induced Pancreatic Injury in Rats.

8. We hypothesize that inside-outside transport of leukotriene C4 (LTC4) via MRP1 is a substantial proatherogenic mechanism in the vasculature.

9. Objective To determine whether leukotriene B4 (LTB4) could directly stimulate human osteoclast differentiation and activation independent of RANKL (ODF).

10. CONCLUSION:Leukotriene inhibitors is safe and effective in clinical use and may be as an new agent in the treatment of asthma.

11. Objective To explore the clinical significance of urinary leukotriene E4 (LTE4) detection in children with respiratory syncytial virus bronchiolitis (RSV).

12. Methods 5- LO products, leukotriene B4 (LTB4) and 5 hydroxyeicosatetraenoic(5-HETE), we re determined by RP-HPLC to represent 5-LO activity.

13. Objective To observe the effect of mizolastine on leukotriene B4(LTB4) and interleukin 5(IL 5) released by spleen lymphocytes of allergic mice challenged by ovalbumin(OVA).

14. Objective To explore the relationship of inflammation mediator leukotriene E4(LTE4) and nocturnal asthma in 3-6 years old children.

15. Specific receptors for leukotriene C4 LTC4 have been identified on intact smooth muscle cells derived from bovine cerebral microvasculatures.

16. A variant of the leukotriene C4 synthase (LTC4S) gene that is linked to asthma susceptibility confers an increased risk of heart disease in women(), say US researchers.

17. The leukotriene modifiers are the drugs that treats almost all the symptoms of allergic rhinitis.

18. OBJECTIVE:To review the progress of leukotriene inhibitors in the treatment of asthma.

19. Objective:To investigate the relationship between serum leukotriene B4 and the development of chronic urticaria.

20. Leukotriene receptor antagonist is a new drug to treat allergic rhinitis.

21. Serum levels of leukotriene D4 by ELISA or enzyme-linked immunosorbent assay.

22. Objective To explore the role of leukotriene B4 in the pathogenesis of chronic urticaria and the anti-inflammation activity of mizolastine in treating chronic urticaria.

23. During the initial phase, newly formed mast cell components such as histamine, serotonin, prostaglandins, and leukotrienes may be released.

24. This topic research the inhibitory effect of Chinese Angelica Decoction(CAD) on LPR of CU and leukotriene B4 which is a very important inflammatory mediator in the LPR of CU.

25. Objective: To study action of Cryptoporus volvatus ferment substance ( CVFS ) on leukotriene production of polymorphonuclear leukocytes in rats.