1. Objective Study on the changes of Orphanin FQ in the plasma and nephridium organizes of rat with Brian trauma, and to explore the effects of Orphanin FQ on acute nephridium injury.

2. The primordial gonad, genital fold which composed of epithelial cells formed below the nephridium area 12 days after hatching.

3. Conclusion The parameter of platelet are important consult of judgment malady, injury of heart, liver nephridium and platelet count was correlation.

4. Conclusion Orphanin FQ may be an important factor in the process of acute nephridium injury after brian trauma.

5. KGF plays an important role in the growth and rebirth of epidermal cell. It can accelerate the bladder, nephridium, intestines and corneal epidermal wound healing.

6. Methods build up a model of rat with brian trauma, and then determined the Levels of Orphanin FQ in the plasma and nephridium organizes by RIA method.