1 Vinblastine is one of the alkaloids from catharanthus roseus.

2 FDA approves vincristine, a sister drug to vinblastine.

3 Several semisynthesis vinblastine analogues were prepared and lots of them have pharmacological activities, some even changed significantly.

4 Antitumor drug vinorelbine tartrate was synthesised from vinblastine sulfate in 15.

5 For local lesions, injection therapy with vinblastine has been used with some success.

6 OBJECTIVE To examine drug release profile of vinblastine sulfate(VBL)thermosensitive hydrogels and evaluate its anti-angiogenic activity.

7 The vinblastine content was increased markedly in the supplementary UV-B radiation, and which were increased further when the nitrogen supply increased.

8 Objective To investigate whether low dose vinblastine (VBL) could inhibit migration and tubular morphogenesis of ECV-304 cells in vitro.

9 Conclusions The process is simple and reasonable with good reproducibility. It is effective to enrich highly purified vinblastine and vincristine.

10 Objective To establish TK gene mutation assay using human lymphoblastoid cell line TK6 and to study the genotoxic mechanism of Vinblastine(VBL).

11 Objective To optimize the technological parameters of separation and purification of vinblastine and vincristine from Gatharanthus Roseus.

12 There are more than 100 kinds of alkaloids in vinca plant, including anhydrovinblastine, vinblastine, vincristine and other anti-tumor medicine used in clinic, etc.

13 The forming and distribution of total flavone content and vinblastine were influenced by different habitat terms and seasonal variation.

14 Objective To investigate the optimal condition for complete removal of the template molecules from vinblastine(VLB)-imprinted polymer.

15 Suitable stress is advantageous to the formation and the accumulation of vinblastine in the Catharanthus roseus.