1. Lipofuscin is called aged pigment, it can deposit on the skin of the elderly ceaselessly and form senile speckles or senile plaques.

2. Methods Contents of malon-dialdehyde(MDA), superoxide dismutase(SOD) and lipofuscin in the heart, liver, brain and kidney of mice were measured using TBA, NBT and fluorescent technique respectively.

3. The content of lipofuscin(LF) estimated for brain and heart of mice. The stress power was observed. The ability of anti tired and tolerance hypoxia and phago-function of macrophage were estimated.

4. Accumulation of ubiquitinated protein and lipofuscin, as well as comprehensive gene expression profiling, indicated that dysregulation of protein quality control was a characteristic of cardiac aging.

5. The content of MDA in serum and lipofuscin in liver homogenate and the activity of T SOD in serum were detected.

6. Ginger: Ginger contains a variety of active ingredients, including the spicy ginger known as a strong role against lipofuscin.

7. It could be found there were pyknosis of neuron, depolymerization of ribosome, accumulation of lipid droplets and lipofuscin, condensation of chromatin.

8. Eliminate free radical, improve immunity, optimize internal secretion, resist lipofuscin and keep nutrient balance.

9. With sufficient funding, the focus on atherosclerosis would be broadened so that neurodegeneration, macular degeneration and lipofuscin accumulation would all also be targeted simultaneously.

10. Eggplant also scattered congestion, eat eggplant, can reduce the probability of blood clots and reduce the deposition of lipofuscin, age spots will be significantly reduced.

11. In this paper, we took the housefly as the experimental animal model to study the effect of Lentinan on SOD activity and lipofuscin content in housefly brain, and on the housefly lifespan.

12. Conclusion: Arctium lappa L. has the remarkable effect of anti-decrepitude, whose main mechanism is to improve the activity of SOD and reduce the content of MDA and lipofuscin.

13. Objective To explore the effect of pinealectomy on content of cerebral neurotic lipofuscin in aged rats.

14. Conclusions These results suggest that the decrease of spiral ganglion cells and the deposition of lipofuscin in the aged may be the main cause of presbycusis .

15. Suppression of target of rapamycin, a downstream effector of phosphoinositide 3-kinase(), also prevented lipofuscin accumulation in the heart.

16. Results Triglyceride droplets and giant mitochondrias were observed in hepatic cells, mitochondrias were damaged and lipofuscin increase in neurotic cells, observed apoptosis in both cells.

17. Results PmTe can effectively increase the moisture of keratoderma, decrease the lipofuscin in keratinized cell.

18. RESULTS:Phosphatidyl choline(PC) could increase the activity of SOD in heart and brain tissues, decreased the content of LPO and lipofuscin.

19. After Drosophila melanogaster were treated with F21 (0.2% concentration), the content of Lipofuscin obviously decreased compared to control group, while the flight frequency obviously increased.

20. Results: For the neuron, we can find pyknosis of neuron, depolymerization of ribosome, accumulation of lipid droplets and lipofuscin, condensation of chromatin.

21. Results The chemoprophylaxis group and the medication group indicate an obvious increase of SOD activation in mice skin and of a reduction of lipofuscin content.

22. METHODS:Mice were used as experimental animals, to determine the activity of superoxide dismutase(SOD) and the content of lipid peroxide(LPO) and lipofuscin.