(1) Contrast to these antimitotic drugs, taxol, the first compound known to interact exclusively with a polymer form of tubulin, works through bind tightly to microtubules and stabilize them.

(2) As a kind of antimitotic drugs, Vinca alkaloids can inhibit microtubule assembly and induce tubulin self-association into coiled spiral aggregates.

(3) As an antimitotic drug it can inhibit microtubule assembly and induce tubulin self-association into coiled spiral aggregates.

(4) Objective conidia of Pyricularia Oryzae to the screening of antimitotic constituents from marine animal sea hare.

(5) Objective:To apply conidia of Pyricularia Oryzae to the screening of antimitotic constituents from marine animal sea hare.

(6) It was found that 303(29.1%) strains of marine microorganisms had antimicrobial activity and 219(21.0%) strains had antimitotic activity.

(7) Conclusion: The proportions of strains with antimicrobial activities and antimitotic activities are both above 20%, suggesting that the East China Sea has rich resources of medicinal microorganisms.